4'-Ethynyl-2'-deoxyadenosine

Modify Date: 2024-01-12 12:32:07

4'-Ethynyl-2'-deoxyadenosine structure	Common Name	4'-Ethynyl-2'-deoxyadenosine
	CAS Number	306305-07-7	Molecular Weight	275.26
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₃N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 4'-Ethynyl-2'-deoxyadenosine

4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity[1].

Name	4'-Ethynyl-2'-deoxyadenosine

Description	4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Reverse Transcriptase
Target	EC50: 98 nM (MT-4 cells)[1].
References	[1]. Ohrui H, et al. 4'-C-substituted-2'-deoxynucleosides: a family of antiretroviral agents which are potent against drug-resistant HIV variants. Curr Drug Targets Infect Disord. 2001 May;1(1):1-10.

Molecular Formula	C₁₂H₁₃N₅O₃
Molecular Weight	275.26

Hazard Codes	Xi

4'-Ethynyl-2'-deoxyadenosine

Use of 4'-Ethynyl-2'-deoxyadenosine

Names

4'-Ethynyl-2'-deoxyadenosine Biological Activity

Chemical & Physical Properties

Safety Information