Dexamethasone Phosphate
Dexamethasone Phosphate structure
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Common Name | Dexamethasone Phosphate | ||
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| CAS Number | 312-93-6 | Molecular Weight | 472.44100 | |
| Density | 1.45g/cm3 | Boiling Point | 669.6ºC at 760mmHg | |
| Molecular Formula | C22H30FO8P | Melting Point | 154-157°C (lit.) | |
| MSDS | N/A | Flash Point | 358.7ºC | |
Use of Dexamethasone PhosphateDexamethasone phosphate (Dexamethasone 21-phosphate) is a biologically inactive compound which undergoes dephosphorylation by intra-erythrocyte enzymes. The active metabolite, dexamethasone, is then released into the circulation by simple passive diffusion through cell membranes. Dexamethasone phosphate-encapsulated erythrocyte has the potential for steroid-dependent ulcerative colitis research[1]. |
Summary: Dexamethasone phosphate (CAS number: 312-93-6) is a synthetic adrenal corticosteroid with potent anti-inflammatory properties. Its molecular formula is C22H30FO8P and molecular weight is 472.44100. It is a white to light brown solid with a melting point of 154-157°C. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | dexamethasone phosphate |
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| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Dexamethasone phosphate (Dexamethasone 21-phosphate) is a biologically inactive compound which undergoes dephosphorylation by intra-erythrocyte enzymes. The active metabolite, dexamethasone, is then released into the circulation by simple passive diffusion through cell membranes. Dexamethasone phosphate-encapsulated erythrocyte has the potential for steroid-dependent ulcerative colitis research[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.45g/cm3 |
|---|---|
| Boiling Point | 669.6ºC at 760mmHg |
| Melting Point | 154-157°C (lit.) |
| Molecular Formula | C22H30FO8P |
| Molecular Weight | 472.44100 |
| Flash Point | 358.7ºC |
| Exact Mass | 472.16600 |
| PSA | 151.17000 |
| LogP | 2.01270 |
| Index of Refraction | 1.594 |
| InChIKey | VQODGRNSFPNSQE-CXSFZGCWSA-N |
| SMILES | CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)COP(=O)(O)O |
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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Dexamethasone P... CAS#:312-93-6 |
| Literature: Chemical and Pharmaceutical Bulletin, , vol. 22, # 7 p. 1439 - 1450 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 1 | |
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| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2937290090 |
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This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Hexadrol phosphate |
| dexamethasone-21-phosphate |
| Dexamethasone 21-orthophosphate |
| Betnelan phosphate |
| Dexamethasone-21-dihydrogen-phosphate |
| Wymesone |
| Neodecadron |
| Oradexon phosphate |
| Dexamethasone phosphate |
| [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] dihydrogen phosphate |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the boiling point of dexamethasone phosphate? |
| A: Boiling point of dexamethasone phosphate is 669.6ºC at 760mmHg. |
| Q: What is the LogP of dexamethasone phosphate? |
| A: LogP of dexamethasone phosphate is 2.01270. |
| Q: What English synonyms does dexamethasone phosphate have? |
| A: English synonyms of dexamethasone phosphate: Hexadrol phosphate, dexamethasone-21-phosphate, Dexamethasone 21-orthophosphate, Betnelan phosphate, Dexamethasone-21-dihydrogen-phosphate, Wymesone, Neodecadron, Oradexon phosphate, Dexamethasone phosphate, [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] dihydrogen phosphate. |
| Q: What is the melting point of dexamethasone phosphate? |
| A: Melting point of dexamethasone phosphate is 154-157°C (lit.). |
| Q: What is the polar surface area (PSA) of dexamethasone phosphate? |
| A: Polar surface area (PSA) of dexamethasone phosphate is 151.17000. |
| Q: What is the English name of dexamethasone phosphate? |
| A: The English name of dexamethasone phosphate is dexamethasone phosphate. |
| Q: What are the upstream materials of dexamethasone phosphate? |
| A: Related upstream materials(CAS) of dexamethasone phosphate: 50-02-2. |
| Q: What is the SMILES notation of dexamethasone phosphate? |
| A: SMILES notation of dexamethasone phosphate is CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)COP(=O)(O)O. |
| Q: What is the InChIKey of dexamethasone phosphate? |
| A: InChIKey of dexamethasone phosphate is VQODGRNSFPNSQE-CXSFZGCWSA-N. |
| Q: What is the molecular weight of dexamethasone phosphate? |
| A: Molecular weight of dexamethasone phosphate is 472.44100. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |