4-Octyl Itaconate

Modify Date: 2024-01-03 12:36:38

4-Octyl Itaconate Structure
4-Octyl Itaconate structure
Common Name 4-Octyl Itaconate
CAS Number 3133-16-2 Molecular Weight 242.31
Density N/A Boiling Point N/A
Molecular Formula C13H22O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4-Octyl Itaconate


4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

 Names

Name 3-octan-4-yloxycarbonylbut-3-enoate
Synonym More Synonyms

 4-Octyl Itaconate Biological Activity

Description 4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Related Catalog
Target

Nrf2[1]

In Vivo 4-Octyl Itaconate (OI) is a cell-permeable itaconate derivative. 4-Octyl Itaconate is protective against lipopolysaccharide-induced lethality in vivo and decreases cytokine production[1].
References

[1]. Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117.

 Chemical & Physical Properties

Molecular Formula C13H22O4
Molecular Weight 242.31
PSA 66.43000
LogP 1.58470
Storage condition 2-8℃

 Synonyms

Butanedioic acid,methylene-,4-octyl ester
4-Octyl Itaconate