L(+)-Ornithine hydrochloride

Modify Date: 2025-08-20 16:48:46

L(+)-Ornithine hydrochloride structure	Common Name	L(+)-Ornithine hydrochloride
	CAS Number	3184-13-2	Molecular Weight	168.622
	Density	1.57	Boiling Point	308.7ºC at 760 mmHg
	Molecular Formula	C₅H₁₃ClN₂O₂	Melting Point	245 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	140.5ºC

Use of L(+)-Ornithine hydrochloride

L-Ornithine Hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

Name	L(+)-Ornithine hydrochloride
Synonym	More Synonyms

Description	L-Ornithine Hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.
Related Catalog	Natural Products >> Others Research Areas >> Metabolic Disease
Target	Human Endogenous Metabolite
References	[1]. Demura S, et al. Effect of L-ornithine hydrochloride ingestion on intermittent maximal anaerobic cycle ergometer performance and fatigue recovery after exercise. Eur J Appl Physiol. 2011 Nov;111(11):2837-43.

Density	1.57
Boiling Point	308.7ºC at 760 mmHg
Melting Point	245 °C (dec.)(lit.)
Molecular Formula	C₅H₁₃ClN₂O₂
Molecular Weight	168.622
Flash Point	140.5ºC
Exact Mass	168.066559
PSA	89.34000
LogP	1.33980
Index of Refraction	24 ° (C=4, 6mol/L HCl)

L(+)-Ornithine hydrochloride MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RM2985000

CHEMICAL NAME :: Ornithine, monohydrochloride, L-

CAS REGISTRY NUMBER :: 3184-13-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C5-H12-N2-O2.Cl-H

MOLECULAR WEIGHT :: 168.65

WISWESSER LINE NOTATION :: Z3YZVQ &GH -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 gm/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 62,49,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4776 No. of Facilities: 162 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 2955 (estimated) No. of Female Employees: 2312 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	RM2985000
HS Code	2922499990

1,1-dimethyleth...

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L(+)-Ornithine ...

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Literature: European Journal of Organic Chemistry, , # 21 p. 4391 - 4396

tert-butyl (2S)...

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L(+)-Ornithine ...

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Literature: European Journal of Organic Chemistry, , # 21 p. 4391 - 4396

Ornithin-t-buty...

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L(+)-Ornithine ...

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Literature: Siebum, Arjan H. G.; Tsang, Robert K. F.; Van Der Steen, Rob; Raap, Jan; Lugtenburg, Johan European Journal of Organic Chemistry, 2004 , # 21 p. 4391 - 4396

L-Arginine hydr...

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Urea

CAS#:57-13-6

Literature: Journal of Chemical Thermodynamics, , vol. 25, # 2 p. 293 - 305

Precursor 4
CAS#:271601-28-6 1,1-dimethyleth... CAS#:824956-17-4 tert-butyl (2S)... CAS#:26302-89-6 Ornithin-t-buty... CAS#:1119-34-2 L-Arginine hydr...
DownStream 10
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3184-13-2 preparation

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma.

Am. J. Respir. Cell. Mol. Biol. 48(6) , 694-702, (2013)

Up-regulation of arginase contributes to airways hyperresponsiveness (AHR) in asthma by reducing L-arginine bioavailability for the nitric oxide (NO) synthase isozymes. The product of arginase activit...

Microbacterium kyungheense sp. nov. and Microbacterium jejuense sp. nov., isolated from salty soil.

Int. J. Syst. Evol. Microbiol. 64(Pt 7) , 2267-73, (2014)

Two novel strains, THG-C26(T) and THG-C31(T), were characterized using a polyphasic approach to determine their taxonomic positions. These two isolates were aerobic, Gram-stain-positive, non-motile, n...

Treatment of arginase deficiency revisited: guanidinoacetate as a therapeutic target and biomarker for therapeutic monitoring.

Dev. Med. Child Neurol. 56(10) , 1021-4, (2014)

Hyperargininaemia is a disorder of the last step of the urea cycle. It is an autosomal recessive disease caused by deficiency of liver arginase-1 and usually presents later in childhood with progressi...

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L(+)-Ornithine hydrochloride

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