L-Ornithine L-aspartate salt

Modify Date: 2024-01-02 18:28:16

L-Ornithine L-aspartate salt structure	Common Name	L-Ornithine L-aspartate salt
	CAS Number	3230-94-2	Molecular Weight	265.264
	Density	N/A	Boiling Point	308.7ºC at 760 mmHg
	Molecular Formula	C₉H₁₉N₃O₆	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	140.5ºC

Use of L-Ornithine L-aspartate salt

L-Ornithine L-aspartate is a stable salt of two natural nonessential L-amino acids: ornithine and aspartic acid. L-Ornithine L-aspartate lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis[1].

Name	(2S)-2-aminobutanedioic acid,(2S)-2,5-diaminopentanoic acid
Synonym	More Synonyms

Description	L-Ornithine L-aspartate is a stable salt of two natural nonessential L-amino acids: ornithine and aspartic acid. L-Ornithine L-aspartate lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Sikorska H, et al. [Physiological functions of L-ornithine and L-aspartate in the body and the efficacy of administration of L-ornithine-L-aspartate in conditions of relative deficiency]. Pol Merkur Lekarski. 2010 Jun;28(168):490-5.

Boiling Point	308.7ºC at 760 mmHg
Molecular Formula	C₉H₁₉N₃O₆
Molecular Weight	265.264
Flash Point	140.5ºC
Exact Mass	265.127380
PSA	189.96000
LogP	0.11110
Storage condition	2-8°C

L-Ornithine L-aspartate salt MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CI9463000

CAS REGISTRY NUMBER :: 3230-94-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C5-H12-N2-O2.C4-H7-N-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85IPAE "Modern Pharmaceuticals of Japan, III," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1968 Volume(issue)/page/year: -,91,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,164,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,164,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85IPAE "Modern Pharmaceuticals of Japan, III," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1968 Volume(issue)/page/year: -,91,1968

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	CI9463000
HS Code	2922499990

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Modulation of neural activation following treatment of hepatic encephalopathy.

Neurology 80(11) , 1041-7, (2013)

To measure changes in psychometric state, neural activation, brain volume (BV), and cerebral metabolite concentrations during treatment of minimal hepatic encephalopathy.As proof of principle, 22 pati...

L-Ornithine-l-aspartate in the management of hepatic encephalopathy: a meta-analysis.

J. Gastroenterol. Hepatol. 24(1) , 9-14, (2009)

Hepatic encephalopathy continues to be a major clinical problem and the current decade has not witnessed major therapeutic breakthroughs in this area. L-ornithine-l-aspartate (LOLA) is not frequently ...

A double-blind, randomized, placebo-controlled trial of intravenous L-ornithine-L-aspartate on postural control in patients with cirrhosis.

Liver Int. 30(4) , 574-82, (2010)

Hepatic encephalopathy (HE) is a complication of liver disease. Several treatments have been introduced but only L-ornithine-L-aspartate (LOLA) shows proven efficacy. This double-blind, randomized, pl...

L-Ornithine L-Aspartate Salt

L-Ornithine L-Aspartate

L-Ornithine-L-Aspartate

L-Aspartic acid - L-ornithine (1:1)

EINECS 221-772-7

L-OrnithineL-aspartatesalt

(S)-2,5-Diaminopentanoic acid L-aspartate salt

Hepa-Merz (TN)

L-Ornithin-L-aspartat

L-Aspartic acid, compd. with L-ornithine (1:1)

MFCD00058084

(S)-2,5-Diaminopentanoic acid compound with (S)-2-aminosuccinic acid

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: L-Ornithine L-aspartate salt
Price: ￥488.0/25g ￥1198.0/100g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: L-Ornithine L-aspartate
Price:
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: L-Ornithine L-aspartate salt
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: L-Ornithine L-aspartate salt
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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L-Ornithine L-aspartate salt

Use of L-Ornithine L-aspartate salt

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