Remogliflozin A

Modify Date: 2025-09-18 18:56:02

Remogliflozin A Structure
Remogliflozin A structure
 Common Name Remogliflozin A
CAS Number 329045-45-6 Molecular Weight 450.53
Density N/A Boiling Point N/A
Molecular Formula C23H34N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Remogliflozin A


Remogliflozin is a potent and selective inhibitor of SGLT2 (sodium-glucose cotransporter 2) with Kis of 12.4 and 26 nM for human and rat SGLT2, respectively[1].

 Names

Name (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[5-methyl-1-propan-2-yl-4-[(4-propan-2-yloxyphenyl)methyl]pyrazol-3-yl]oxyoxane-3,4,5-triol
Synonym More Synonyms

 Remogliflozin A Biological Activity

Description Remogliflozin is a potent and selective inhibitor of SGLT2 (sodium-glucose cotransporter 2) with Kis of 12.4 and 26 nM for human and rat SGLT2, respectively[1].
Related Catalog
References

[1]. Fujimori Y, et al. Remogliflozin etabonate, in a novel category of selective low-affinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models. J Pharmacol Exp Ther. 2008 Oct;327(1):268-76.

 Chemical & Physical Properties

Molecular Formula C23H34N2O7
Molecular Weight 450.53
Exact Mass 450.23700
PSA 126.43000
LogP 1.32910

 Synthetic Route

(2R,3R,4S,5R,6S)-2-(acetoxymethyl)-6-((4-(4-isopropoxybenzyl)-1-isopropyl-5-methyl-1H-pyrazol-3-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate structure

(2R,3R,4S,5R,6S...

CAS#:1338796-70-5

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Remogliflozin A Structure

Remogliflozin A

CAS#:329045-45-6

Literature: GLAXOSMITHKLINE LLC; MARTIN, Michael Tolar; MCCLURE, Michael S; ELITZIN, Vassil Patent: WO2010/59774 A1, 2010 ; Location in patent: Page/Page column 26-27 ; WO 2010/059774 A1

 Synonyms

Remogliflozin A
UNII-13ZPK7A4MJ
[14C]-Remogliflozin
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