Ecabet

Modify Date: 2025-08-25 10:16:04

Ecabet structure	Common Name	Ecabet
	CAS Number	33159-27-2	Molecular Weight	380.49800
	Density	1.241 g/cm3	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₈O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Ecabet

Ecabet sodium (TA-2711) is currently applied to some clinical gastrointestinal disease by inhibiting the ROS production and improving Helicobacter pylori eradication[1]. Ecabet sodium reduces apoptosis[2]

Name	(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-6-sulfo-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid
Synonym	More Synonyms

Description	Ecabet sodium (TA-2711) is currently applied to some clinical gastrointestinal disease by inhibiting the ROS production and improving Helicobacter pylori eradication[1]. Ecabet sodium reduces apoptosis[2]
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Wang Y, et al. Efficacy and safety of ecabet sodium as an adjuvant therapy for Helicobacter pylori eradication: a systematic review and meta-analysis. Helicobacter. 2014 Oct;19(5):372-81. [2]. Rah YC, et al. Ecabet sodium alleviates neomycin-induced hair cell damage. Free Radic Biol Med. 2015 Dec;89:1176-83.

Description

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. Wang Y, et al. Efficacy and safety of ecabet sodium as an adjuvant therapy for Helicobacter pylori eradication: a systematic review and meta-analysis. Helicobacter. 2014 Oct;19(5):372-81.

[2]. Rah YC, et al. Ecabet sodium alleviates neomycin-induced hair cell damage. Free Radic Biol Med. 2015 Dec;89:1176-83.

Density	1.241 g/cm3
Molecular Formula	C₂₀H₂₈O₅S
Molecular Weight	380.49800
Exact Mass	380.16600
PSA	100.05000
LogP	5.23240
Index of Refraction	1.562
InChIKey	IWCWQNVIUXZOMJ-MISYRCLQSA-N
SMILES	CC(C)c1cc2c(cc1S(=O)(=O)O)C1(C)CCCC(C)(C(=O)O)C1CC2

Hazard Codes	Xi

dehydroabietic acid

CAS#:1740-19-8

Ecabet

CAS#:33159-27-2

Literature: Journal of the American Chemical Society, , vol. 63, p. 1759 Journal of the American Chemical Society, , vol. 61, p. 247 Journal of the American Chemical Society, , vol. 63, p. 1838,1841 Journal of the American Chemical Society, , vol. 60, p. 2631,2633 Journal of the American Chemical Society, , vol. 61, p. 2528,2530

abietic acid

CAS#:514-10-3

Ecabet

CAS#:33159-27-2

Literature: Journal of the American Chemical Society, , vol. 61, p. 247 Journal of the American Chemical Society, , vol. 60, p. 2631,2633 Journal of the American Chemical Society, , vol. 61, p. 2528,2530

Precursor 2
CAS#:1740-19-8 dehydroabietic acid CAS#:514-10-3 abietic acid
DownStream 1
CAS#:1740-19-8 dehydroabietic acid

Name: Compound was evaluated for inhibition of rat Gabra1 in an in vitro assay with cellula...
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit alpha-1
External Id: CHEMBL5291801

Name: Binding affinity towards rat Gabra1 in an in vitro assay with cellular components mea...
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit alpha-1
External Id: CHEMBL5291798

Name: Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020);...
Source: ChEMBL
Target: Staphylococcus aureus
External Id: CHEMBL4296184

Name: Binding affinity towards human ESR1 in an in vitro cell free assay (NIBR assay) measu...
Source: ChEMBL
Target: Estrogen receptor
External Id: CHEMBL5291791

Name: Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
Source: ChEMBL
Target: Klebsiella pneumoniae
External Id: CHEMBL4296186

Name: Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CA...
Source: ChEMBL
Target: Escherichia coli
External Id: CHEMBL4296185

Name: Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry
Source: NCGC
Target: N/A
External Id: TRND-SARS-CoV-2-cytotox-48hr

Name: Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry
Source: NCGC
External Id: TRND-SARS-CoV-2-PP

Name: Binding affinity towards human EDNRA in an in vitro assay with cellular components me...
Source: ChEMBL
Target: Endothelin-1 receptor
External Id: CHEMBL5291785

Name: Binding affinity towards human DRD2 in an in vitro assay with cellular components mea...
Source: ChEMBL
Target: D(2) dopamine receptor
External Id: CHEMBL5291781

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Ecabet

sulfodehydroabietic acid

Ecabetum

Gastrom

12-sulfodehydroabietic acid

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Ecabet
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Amole Biotechnology Co., Ltd.
China
Product Name: Ecabet
Price: ￥Inquiry/100mg ￥Inquiry/1g ￥Inquiry/250mg ￥Inquiry/5g
Purity: 95.0%
Delivery: Inquiry
Contact: Xiyao Wang
Email: 3623107365@qq.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.