CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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XH8380000
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CHEMICAL NAME :
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4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-phenylacetamido)-3,3- dimethyl-7-oxo-, hydroxymethyl ester, pivalate (ester), D-(-)-
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CAS REGISTRY NUMBER :
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33817-20-8
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LAST UPDATED :
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199706
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C22-H29-N3-O6-S
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MOLECULAR WEIGHT :
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463.60
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WISWESSER LINE NOTATION :
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T45 ANV ESTJ CMVYZR& F1 F1 GVO1OVX1&1&1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human - woman
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DOSE/DURATION :
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900 mg/kg/90D-I
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TOXIC EFFECTS :
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Behavioral - muscle weakness Musculoskeletal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
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REFERENCE :
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PGMJAO Postgraduate Medical Journal. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1925- Volume(issue)/page/year: 68,932,1992
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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>6 gm/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JOPHDQ Journal of Pharmacobio-Dynamics. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1978- Volume(issue)/page/year: 1,310,1978
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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148 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JOPHDQ Journal of Pharmacobio-Dynamics. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1978- Volume(issue)/page/year: 1,310,1978
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CAS#:69-53-4