SIRT1-IN-1

Modify Date: 2024-01-10 04:21:54

SIRT1-IN-1 structure	Common Name	SIRT1-IN-1
	CAS Number	352554-02-0	Molecular Weight	228.29
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₆N₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SIRT1-IN-1

SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM[1]. SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity[2].

Name	SIRT1-IN-1

Description	SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM[1]. SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity[2].
Related Catalog	Signaling Pathways >> Epigenetics >> Sirtuin Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin Signaling Pathways >> Anti-infection >> CMV
Target	SIRT1:0.205 μM (IC50) SIRT2:11.5 μM (IC50) SIRT3:>100 μM (IC50)
In Vitro	SIRT1-IN-1 (compound 2) has little effect on SIRT3 (IC50>100 μM) and HDAC (IC50>100 μM)[1].
References	[1]. Andrew D Napper, et al. Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54. [2]. Thomas Shenk, et al. Sirtuin Modulators as Inhibitors of Cytomegalovirus. US20160296523A1.

Molecular Formula	C₁₄H₁₆N₂O
Molecular Weight	228.29

DC Chemicals Limited
China
Product Name: SIRT1-IN-1
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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