SIRT1-IN-1
Modify Date: 2024-01-10 04:21:54
SIRT1-IN-1 structure
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Common Name | SIRT1-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 352554-02-0 | Molecular Weight | 228.29 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H16N2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SIRT1-IN-1SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM[1]. SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity[2]. |
| Name | SIRT1-IN-1 |
|---|
| Description | SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM[1]. SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity[2]. |
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| Related Catalog | |
| Target |
SIRT1:0.205 μM (IC50) SIRT2:11.5 μM (IC50) SIRT3:>100 μM (IC50) |
| In Vitro | SIRT1-IN-1 (compound 2) has little effect on SIRT3 (IC50>100 μM) and HDAC (IC50>100 μM)[1]. |
| References |
[2]. Thomas Shenk, et al. Sirtuin Modulators as Inhibitors of Cytomegalovirus. US20160296523A1. |
| Molecular Formula | C14H16N2O |
|---|---|
| Molecular Weight | 228.29 |