Dehydroleucodine

Modify Date: 2024-04-02 23:36:43

Dehydroleucodine Structure
Dehydroleucodine structure
Common Name Dehydroleucodine
CAS Number 36150-07-9 Molecular Weight 244.28600
Density 1.2g/cm3 Boiling Point 450.6ºC at 760mmHg
Molecular Formula C15H16O3 Melting Point N/A
MSDS Chinese USA Flash Point 203.1ºC

 Use of Dehydroleucodine


Dehydroleucodine is a sesquiterpene lactone isolated from Gynoxys verrucosa. Dehydroleucodine is a mast cell stabilizer that inhibits tmast cell degranulation induced by compound 48/80. Dehydroleucodine inudces cells apoptosis, and has gastric ulcer inhibition and antileukemic effects[1][2][3].

 Names

Name Dehydroleucodine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2g/cm3
Boiling Point 450.6ºC at 760mmHg
Molecular Formula C15H16O3
Molecular Weight 244.28600
Flash Point 203.1ºC
Exact Mass 244.11000
PSA 43.37000
LogP 2.33970
Index of Refraction 1.562

 Safety Information

RIDADR NONH for all modes of transport

 Articles23

More Articles
Antidiarrheal activity of dehydroleucodine isolated from Artemisia douglasiana.

Fitoterapia 79(1) , 1-5, (2008)

Dehydroleucodine (DhL), a sesquiterpene lactone obtained from Artemisia douglasiana, was screened for antidiarrheal effects. DhL inhibited castor oil-induced diarrhea in mice by judged by a decrease i...

Role of mast cells in gastrointestinal mucosal defense.

Biocell 27(2) , 163-72, (2003)

The purpose of this review, based on studies from our laboratory as well as from others, is to summarize salient features of mast cell immunobiology and to describe their associations with gastrointes...

Effect of dehydroleucodine on intestinal transit: structural basis of the interaction with the α(2)-adrenergic receptor.

Eur. Biophys. J. 40(8) , 981-6, (2011)

The activity of dehydroleucodine, a sesquiterpene lactone obtained from Artemisia douglasiana, was studied in mice small intestinal transit. Its mechanism was evaluated in the presence of several adre...

 Synonyms

DEHYDROACHILLIN
11,13-Dehydroleucodin Dehydroleucodin Leucodin Lidbeckialactone Mesatlantin E
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