2-Methoxy estrone
2-Methoxy estrone structure
|
Common Name | 2-Methoxy estrone | ||
|---|---|---|---|---|
| CAS Number | 362-08-3 | Molecular Weight | 300.392 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 463.5±45.0 °C at 760 mmHg | |
| Molecular Formula | C19H24O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 165.9±22.2 °C | |
| Symbol |
GHS08, GHS09 |
Signal Word | Warning | |
Use of 2-Methoxy estrone2-Methoxyestrone is a methoxylated catechol estrogen and metabolite of estrone, with a pKa of 10.81. |
Summary: 2-methoxyestrone (CAS number: 362-08-3) is a methoxyphenol estrogen and a metabolite of estrone, with molecular formula C19H24O3. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-methoxyestrone |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 2-Methoxyestrone is a methoxylated catechol estrogen and metabolite of estrone, with a pKa of 10.81. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 463.5±45.0 °C at 760 mmHg |
| Molecular Formula | C19H24O3 |
| Molecular Weight | 300.392 |
| Flash Point | 165.9±22.2 °C |
| Exact Mass | 300.172546 |
| PSA | 46.53000 |
| LogP | 3.39 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.576 |
| InChIKey | WHEUWNKSCXYKBU-QPWUGHHJSA-N |
| SMILES | COc1cc2c(cc1O)CCC1C2CCC2(C)C(=O)CCC12 |
| Storage condition | 2-8℃ |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS08, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H351-H410 |
| Precautionary Statements | P273-P281-P501 |
| Hazard Codes | Xn: Harmful;N: Dangerous for the environment; |
| Risk Phrases | 40-50/53 |
| Safety Phrases | 22-36-61-60 |
| RIDADR | UN3077 9/PG 3 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 10 | |
|---|---|
| DownStream 5 | |
CAS#:362-07-2![[(8R,9S,13S,14S)-2-methoxy-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] acetate Structure](https://image.chemsrc.com/caspic/391/83649-26-7.png)
CAS#:83649-26-7
CAS#:42979-88-4
CAS#:124-41-4
CAS#:65932-53-8
CAS#:5976-64-7
CAS#:863015-89-8
CAS#:874920-40-8
CAS#:700369-39-7
CAS#:53-16-7
CAS#:362-06-1
CAS#:50394-89-3
CAS#:22415-44-7
CAS#:127349-68-2This table lists relevant public references with title, journal and publication metadata for this compound.
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An UPLC-MS-based metabolomics investigation on the anti-fatigue effect of salidroside in mice.
J. Pharm. Biomed. Anal. 105 , 84-90, (2015) An ultra-performance liquid chromatography-quadrupole time-of-flight-based metabolomic approach was developed to study influence of salidroside, an anti-fatigue ingredient from Rhoiola rosea, on urina... |
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Study of urinary steroid hormone disorders: difference between hepatocellular carcinoma in early stage and cirrhosis.
Anal. Bioanal. Chem 406(18) , 4325-35, (2014) Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world. Discovery of novel biomarkers for early HCC from other liver diseases such as cirrhosis is of great clinical benefit. In th... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2-Methoxy Estrone |
| 2-METHOXYESTRONE |
| 3-hydroxy-2-methoxy-Estra-1,3,5(10)-trien-17-one |
| (8R,9S,13S,14S)-3-hydroxy-2-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one |
| 2-Methoxy-17-oxoestra-1,3,5(10)-trien-3-ol |
| 3-Hydroxy-2-methoxyestra-1,3,5(10)-trien-17-one |
| 2-Methoxy-3-hydroxyestra-1,3,5(10)-trien-17-one |
| 2-MeO-E1 3-Hydroxy-2-methoxyestra-1,3,5(10)-trien-17-one |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the upstream materials of 2-methoxyestrone? |
| A: Related upstream materials(CAS) of 2-methoxyestrone: 362-07-2;83649-26-7;42979-88-4;124-41-4;65932-53-8;5976-64-7;863015-89-8;874920-40-8;700369-39-7;53-16-7. |
| Q: What are the storage conditions for 2-methoxyestrone? |
| A: Storage conditions for 2-methoxyestrone: 2-8℃. |
| Q: What is the molecular formula of 2-methoxyestrone? |
| A: Molecular formula of 2-methoxyestrone is C19H24O3. |
| Q: What is the SMILES notation of 2-methoxyestrone? |
| A: SMILES notation of 2-methoxyestrone is COc1cc2c(cc1O)CCC1C2CCC2(C)C(=O)CCC12. |
| Q: What are the uses of 2-methoxyestrone? |
| A: Main uses of 2-methoxyestrone: 2-Methoxyestrone is a methoxylated catechol estrogen and metabolite of estrone, with a pKa of 10.81. |
| Q: What is the boiling point of 2-methoxyestrone? |
| A: Boiling point of 2-methoxyestrone is 463.5±45.0 °C at 760 mmHg. |
| Q: What are the downstream products of 2-methoxyestrone? |
| A: Related downstream products(CAS) of 2-methoxyestrone: 362-06-1;362-07-2;50394-89-3;22415-44-7;127349-68-2. |
| Q: What is the polar surface area (PSA) of 2-methoxyestrone? |
| A: Polar surface area (PSA) of 2-methoxyestrone is 46.53000. |
| Q: What is the molecular weight of 2-methoxyestrone? |
| A: Molecular weight of 2-methoxyestrone is 300.392. |
| Q: What is the English name of 2-methoxyestrone? |
| A: The English name of 2-methoxyestrone is 2-methoxyestrone. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |