Ganglioside GM1

Modify Date: 2024-01-02 12:38:50

Ganglioside GM1 Structure
Ganglioside GM1 structure
Common Name Ganglioside GM1
CAS Number 37758-47-7 Molecular Weight 1602.93000
Density 1.35 g/cm3 Boiling Point 1527ºC at 760 mmHg
Molecular Formula C77H139N3O31 Melting Point 207-230ºC
MSDS USA Flash Point 877.3ºC

 Use of Ganglioside GM1


Ganglioside GM1 is a member of the ganglioside family that can be used for neurological disease research. Ganglioside GM1 is a functional tissue receptor for the Cholera Toxin1[1].

 Names

Name ganglioside GM1
Synonym More Synonyms

 Ganglioside GM1 Biological Activity

Description Ganglioside GM1 is a member of the ganglioside family that can be used for neurological disease research. Ganglioside GM1 is a functional tissue receptor for the Cholera Toxin1[1].
Related Catalog
References

[1]. Wenchao Zhang, et al. Pathophysiology of Ganglioside GM1 in Ischemic Stroke: Ganglioside GM1: A Critical Review. Cell Transplant. 2019 Jun;28(6):657-661.  

 Chemical & Physical Properties

Density 1.35 g/cm3
Boiling Point 1527ºC at 760 mmHg
Melting Point 207-230ºC
Molecular Formula C77H139N3O31
Molecular Weight 1602.93000
Flash Point 877.3ºC
Exact Mass 1601.94000
PSA 540.58000
LogP 1.69070
Storage condition −20°C
Water Solubility chloroform/methanol (9:1): 10 mg/mL, clear, colorless

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Risk Phrases R22
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS FK1200000
HS Code 29400090

 Articles52

More Articles
Methylmercury causes neuronal cell death through the suppression of the TrkA pathway: in vitro and in vivo effects of TrkA pathway activators.

Toxicol. Appl. Pharmacol. 282(3) , 259-66, (2015)

Methylmercury (MeHg) is an environmental toxin which induces cell death specific for the nervous systems. Here we show that MeHg causes neuronal cell death through the suppression of the tropomyosin r...

Ganglioside GM1-mediated transcytosis of cholera toxin bypasses the retrograde pathway and depends on the structure of the ceramide domain.

J. Biol. Chem. 288(36) , 25804-9, (2013)

Cholera toxin causes diarrheal disease by binding ganglioside GM1 on the apical membrane of polarized intestinal epithelial cells and trafficking retrograde through sorting endosomes, the trans-Golgi ...

Fuzheng Huayu inhibits carbon tetrachloride-induced liver fibrosis in mice through activating hepatic NK cells.

J. Ethnopharmacol. 145(1) , 175-81, (2013)

Fuzheng Huayu (FZHY) is a Chinese compound herbal preparation which consists of six Chinese herbs. This study examines the preventative effects of FZHY on liver fibrosis induced by carbon tetrachlorid...

 Synonyms

GM1 Ganglioside,Brain,Ovine-Sodium Salt)
Ganglioside GM1,monosialo
GANGLIOSIDE GM1, AMMONIUM SALT, BOVINE
MFCD00466936
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