(Sar1)-Angiotensin II

Modify Date: 2024-01-02 23:53:25

(Sar1)-Angiotensin II Structure
(Sar1)-Angiotensin II structure
Common Name (Sar1)-Angiotensin II
CAS Number 51833-69-3 Molecular Weight 1002.17000
Density N/A Boiling Point N/A
Molecular Formula C49H71N13O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (Sar1)-Angiotensin II


(Sar1)-Angiotensin II, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. (Sar1)-Angiotensin II binds to brain membrane-rich particles, with a Kd of 2.7 nM. (Sar1)-Angiotensin II can stimulate protein synthesis and cell growth in embryonic chick myocytes[1][2][3].

 Names

Name angiotensin II
Synonym More Synonyms

 (Sar1)-Angiotensin II Biological Activity

Description (Sar1)-Angiotensin II, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. (Sar1)-Angiotensin II binds to brain membrane-rich particles, with a Kd of 2.7 nM. (Sar1)-Angiotensin II can stimulate protein synthesis and cell growth in embryonic chick myocytes[1][2][3].
Related Catalog
In Vitro (Sar1)-Angiotensin II (1 μM/day; 9 d) increases the total protein content in embryonic chick myocytes by 18.5, 26.2, and 22.2% at 5, 7, and 9 days, respectively[2]. (Sar1)-Angiotensin II binds to brain membrane-rich particles in cynomolgus monkey brain, with a Kd of 2.7 nM[3].
References

[1]. Matsoukas JM, et, al. Differences in backbone structure between angiotensin II agonists and type I antagonists. J Med Chem. 1995 Nov 10;38(23):4660-9.

[2]. Aceto JF, et, al. [Sar1]angiotensin II receptor-mediated stimulation of protein synthesis in chick heart cells. Am J Physiol. 1990 Mar;258(3 Pt 2):H806-13.

[3]. Millan MA, et, al. Distribution of angiotensin II receptors in the brain of nonhuman primates. Peptides. Mar-Apr 1990;11(2):243-53.

 Chemical & Physical Properties

Molecular Formula C49H71N13O10
Molecular Weight 1002.17000
Exact Mass 1001.54000
PSA 355.05000
LogP 3.17750

 Synonyms

(Sar1)-Angiotensin II