Flavokawain A

Modify Date: 2024-01-10 16:15:29

Flavokawain A Structure
Flavokawain A structure
Common Name Flavokawain A
CAS Number 37951-13-6 Molecular Weight 314.332
Density 1.2±0.1 g/cm3 Boiling Point 529.9±50.0 °C at 760 mmHg
Molecular Formula C18H18O5 Melting Point 114℃
MSDS N/A Flash Point 193.2±23.6 °C

 Use of Flavokawain A


Flavokawain A, a chalcone extracted from Kava, has anticarcinogenic effect. Flavokawain A induces apoptosis in bladder cancer cells by involvement of bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice[1].

 Names

Name Flavokawain A
Synonym More Synonyms

 Flavokawain A Biological Activity

Description Flavokawain A, a chalcone extracted from Kava, has anticarcinogenic effect. Flavokawain A induces apoptosis in bladder cancer cells by involvement of bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice[1].
Related Catalog
References

[1]. Zi X, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 529.9±50.0 °C at 760 mmHg
Melting Point 114℃
Molecular Formula C18H18O5
Molecular Weight 314.332
Flash Point 193.2±23.6 °C
Exact Mass 314.115417
LogP 3.96
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.600

 Synonyms

(2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one
(2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one
1OR CQ EO1 BV1U1R DO1 &&E Form
2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-, (2E)-
MFCD00017174
(E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one
2′-Hydroxy-4,4′,6′-trimethoxychalcone
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