Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Propen-1-one,1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

3420-72-2

3420-72-2 structure

Name: Flavokawain A
Chemical Name: 2'-hydroxy-4,4',6'-trimethoxychalcone
CAS Number: 3420-72-2
Molecular Formula: C₁₈H₁₈O₅
Molecular Weight: 314.332
Catalog: Natural product Chalcone
Create Date: 2018-12-29 18:50:50
Modify Date: 2024-01-02 17:58:04
Flavokawain A, a proming anticarcinogenic agent, is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer[1].

Name	2'-hydroxy-4,4',6'-trimethoxychalcone
Synonyms	FLAVOKAWIN A 1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one Flavokavin A MFCD00017174 2'-Hydroxy-4,4',6'-trimethoxy-trans-chalcone 2'-Hydroxy-4,4',6'-trimethoxy flavokawain-A 2'-hydroxy-4',6'-dimethoxyphenyl-4-methoxystyrylketone 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)- 2'-hydroxy-4,4',6'-trimethoxy-chalcone Flavokawain A

Description	Flavokawain A, a proming anticarcinogenic agent, is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Xiaolin Zi, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2914509090

90-24-4

123-11-5

~82%

3420-72-2

94103-36-3

~89%

3420-72-2

Literature: Lee, Yean-Jang; Wu, Tsao-Dong Journal of the Chinese Chemical Society, 2001 , vol. 48, # 2 p. 201 - 206

621-23-8

34446-64-5

~36%

3420-72-2

Literature: Lee, Yean-Jang; Wu, Tsao-Dong Journal of the Chinese Chemical Society, 2001 , vol. 48, # 2 p. 201 - 206

520-36-5

77-78-1

~49%

3420-72-2

62014-87-3

74-88-4

3420-72-2

Literature: Journal of Agricultural and Food Chemistry, , vol. 48, # 5 p. 1888 - 1891

621-23-8

3420-72-2

Literature: Journal of the Chinese Chemical Society, , vol. 48, # 2 p. 201 - 206

832-58-6

3420-72-2

Literature: Journal of the Chinese Chemical Society, , vol. 48, # 2 p. 201 - 206

480-66-0

3420-72-2

Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, p. 57 - 58

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%