Thalidomide 4'-ether-alkylC2-amine
Modify Date: 2024-01-17 11:04:01
Thalidomide 4'-ether-alkylC2-amine structure
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Common Name | Thalidomide 4'-ether-alkylC2-amine | ||
|---|---|---|---|---|
| CAS Number | 390367-50-7 | Molecular Weight | 317.297 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 612.1±55.0 °C at 760 mmHg | |
| Molecular Formula | C15H15N3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 324.0±31.5 °C | |
Use of Thalidomide 4'-ether-alkylC2-amineThalidomide 4'-ether-alkylC2-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
| Name | 3-(2-Aminoethoxy) Thalidomide |
|---|---|
| Synonym | More Synonyms |
| Description | Thalidomide 4'-ether-alkylC2-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 612.1±55.0 °C at 760 mmHg |
| Molecular Formula | C15H15N3O5 |
| Molecular Weight | 317.297 |
| Flash Point | 324.0±31.5 °C |
| Exact Mass | 317.101166 |
| LogP | -0.79 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.634 |
| Hazard Codes | Xi |
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| 4-(2-Aminoethoxy)-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione |
| 1H-Isoindole-1,3(2H)-dione, 4-(2-aminoethoxy)-2-(2,6-dioxo-3-piperidinyl)- |