2,4-Dichloro-6-methylpyrimidine

Modify Date: 2024-01-02 17:01:46

2,4-Dichloro-6-methylpyrimidine Structure
2,4-Dichloro-6-methylpyrimidine structure
Common Name 2,4-Dichloro-6-methylpyrimidine
CAS Number 5424-21-5 Molecular Weight 163.005
Density 1.4±0.1 g/cm3 Boiling Point 219.0±20.0 °C at 760 mmHg
Molecular Formula C5H4Cl2N2 Melting Point 44-47 °C(lit.)
MSDS Chinese USA Flash Point 107.0±7.4 °C
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name 2,4-Dichloro-6-methylpyrimidine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 219.0±20.0 °C at 760 mmHg
Melting Point 44-47 °C(lit.)
Molecular Formula C5H4Cl2N2
Molecular Weight 163.005
Flash Point 107.0±7.4 °C
Exact Mass 161.975159
PSA 25.78000
LogP 1.62
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.551

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C:Corrosive;
Risk Phrases R34
Safety Phrases S26-S27-S36/37/39-S45
RIDADR UN 3263 8/PG 2
WGK Germany 3
Packaging Group III
Hazard Class 8
HS Code 2933599090

 Synthetic Route

~83%

2,4-Dichloro-6-methylpyrimidine Structure

2,4-Dichloro-6-...

CAS#:5424-21-5

Literature: Hung; Werbel Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 3 p. 741 - 744

~%

2,4-Dichloro-6-methylpyrimidine Structure

2,4-Dichloro-6-...

CAS#:5424-21-5

Literature: Yakugaku Zasshi, , vol. 70, p. 137 Chem.Abstr., , p. 5886

~%

2,4-Dichloro-6-methylpyrimidine Structure

2,4-Dichloro-6-...

CAS#:5424-21-5

Literature: Yakugaku Zasshi, , vol. 70, p. 137 Chem.Abstr., , p. 5886

~%

2,4-Dichloro-6-methylpyrimidine Structure

2,4-Dichloro-6-...

CAS#:5424-21-5

Literature: Yakugaku Zasshi, , vol. 70, p. 137 Chem.Abstr., , p. 5886

~%

2,4-Dichloro-6-methylpyrimidine Structure

2,4-Dichloro-6-...

CAS#:5424-21-5

Literature: Yakugaku Zasshi, , vol. 70, p. 137 Chem.Abstr., , p. 5886

~96%

2,4-Dichloro-6-methylpyrimidine Structure

2,4-Dichloro-6-...

CAS#:5424-21-5

Literature: Journal of Heterocyclic Chemistry, , vol. 24, # 1 p. 205 - 209

~95%

2,4-Dichloro-6-methylpyrimidine Structure

2,4-Dichloro-6-...

CAS#:5424-21-5

Detail
Literature: Journal of Heterocyclic Chemistry, , vol. 24, # 1 p. 205 - 209

~65%

2,4-Dichloro-6-methylpyrimidine Structure

2,4-Dichloro-6-...

CAS#:5424-21-5

Detail
Literature: Journal of Heterocyclic Chemistry, , vol. 21, p. 1161 - 1167

~%

2,4-Dichloro-6-methylpyrimidine Structure

2,4-Dichloro-6-...

CAS#:5424-21-5

Literature: Chemische Berichte, , vol. 32, p. 1533,2930, 2934

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles3

More Articles
4-Arylvinyl-2,6-di(pyridin-2-yl)pyrimidines: synthesis and optical properties.

J. Org. Chem. 76(10) , 3837-45, (2011)

A series of 4-arylvinyl-2,6-di(pyridin-2-yl)pyrimidines have been efficiently prepared by a double cross-coupling reaction between 2,4-dichloro-6-methylpyrimidine and 2-(tributylstannyl)pyridine, foll...

Fluorous synthesis of disubstituted pyrimidines.

Org. Lett. 5(7) , 1011-3, (2003)

[reaction: see text] The fluorous synthesis of disubstituted pyrimidines is carried out by attaching 2,4-dichloro-6-methylpyrimidine with 1H,1H,2H,2H-perfluorodecanethiol. The tagged substrate is subs...

Novel inhibitors of Rac1 in metastatic breast cancer.

P. R. Health Sci. J. 29(4) , 348-56, (2010)

Rho family GTPases are molecular switches that control signaling pathways regulating a myriad of cellular functions. Rac1, a Rho family member, plays a critical role in several aspects of tumorigenesi...

 Synonyms

2,4-dichloro-6-methyl pyrimidine
2,4,5-TRIFLUOROBENZAMIDINE HYDROCHLORIDE
2,4-dichloro-6-methyl-pyrimidine
EINECS 226-563-4
2,4-Dichloro-6-methylpyrimidine
Pyrimidine,2,4-dichloro-6-methyl
MFCD00006064
Pyrimidine, 2,4-dichloro-6-methyl-
2,6-dichloro-4-methylpyrimidine
6-methyl-2,4-dichloropyrimidine
2,4-Dichlor-6-methyl-pyrimidin
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