RUVBL1/2 ATPase-IN-1

Modify Date: 2025-08-25 19:50:47

RUVBL1/2 ATPase-IN-1 Structure
RUVBL1/2 ATPase-IN-1 structure
Common Name RUVBL1/2 ATPase-IN-1
CAS Number 423128-55-6 Molecular Weight 507.55
Density N/A Boiling Point N/A
Molecular Formula C28H28F3N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RUVBL1/2 ATPase-IN-1


RUVBL1/2 ATPase-IN-1 (compound 18) is a potent and selective inhibitor of RUVBL1/2 ATPase with IC50 values of 6.0 and 7.7 μM, respectively. RUVBL1 and RUVBL2 are highly conserved AAA ATPases (ATPases Associated with various cellular Activities) and highly relevant to the progression of cancer. RUVBL1/2 ATPase-IN-1 has the potential for the research of cancer diseases[1].

 Names

Name RUVBL1/2 ATPase-IN-1

 RUVBL1/2 ATPase-IN-1 Biological Activity

Description RUVBL1/2 ATPase-IN-1 (compound 18) is a potent and selective inhibitor of RUVBL1/2 ATPase with IC50 values of 6.0 and 7.7 μM, respectively. RUVBL1 and RUVBL2 are highly conserved AAA ATPases (ATPases Associated with various cellular Activities) and highly relevant to the progression of cancer. RUVBL1/2 ATPase-IN-1 has the potential for the research of cancer diseases[1].
Related Catalog
References

[1]. Zhang G, et al. Discovery of small-molecule inhibitors of RUVBL1/2 ATPase. Bioorg Med Chem. 2022;62:116726.

 Chemical & Physical Properties

Molecular Formula C28H28F3N5O
Molecular Weight 507.55
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