Methyl 5-amino-2-hydroxybenzoate
Methyl 5-amino-2-hydroxybenzoate structure
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Common Name | Methyl 5-amino-2-hydroxybenzoate | ||
|---|---|---|---|---|
| CAS Number | 42753-75-3 | Molecular Weight | 167.162 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 319.2±27.0 °C at 760 mmHg | |
| Molecular Formula | C8H9NO3 | Melting Point | 95-99 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 146.8±23.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Methyl 5-amino-2-hydroxybenzoate |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 319.2±27.0 °C at 760 mmHg |
| Melting Point | 95-99 °C(lit.) |
| Molecular Formula | C8H9NO3 |
| Molecular Weight | 167.162 |
| Flash Point | 146.8±23.7 °C |
| Exact Mass | 167.058243 |
| PSA | 72.55000 |
| LogP | 0.56 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.606 |
| InChIKey | MXUHMQZOATZRIK-UHFFFAOYSA-N |
| SMILES | COC(=O)c1cc(N)ccc1O |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H317-H319-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn |
| Risk Phrases | 22-36/37/38-43 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | VO1683100 |
| HS Code | 2922509090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~98%
Methyl 5-amino-... CAS#:42753-75-3 |
| Literature: Zhou, Lei; Yang, Haishen; Wang, Pengfei Journal of Organic Chemistry, 2011 , vol. 76, # 15 p. 5873 - 5881 |
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~95%
Methyl 5-amino-... CAS#:42753-75-3 |
| Literature: Schmidt, Bernd; Hoelter, Frank; Berger, Rene; Jessel, Soenke Advanced Synthesis and Catalysis, 2010 , vol. 352, # 14-15 p. 2463 - 2473 |
|
~62%
Methyl 5-amino-... CAS#:42753-75-3 |
| Literature: Desreumaux, Pierre; Bellinvia, Salvatore; Chavatte, Philippe; Baroni, Sergio Patent: US2011/39808 A1, 2011 ; Location in patent: Page/Page column 50 ; |
|
~45%
Methyl 5-amino-... CAS#:42753-75-3 |
| Literature: DAK-Laboratoriet Patent: US4933330 A1, 1990 ; |
|
~%
Methyl 5-amino-... CAS#:42753-75-3 |
| Literature: American Cyanamid Company Patent: US4087613 A1, 1978 ; |
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~%
Methyl 5-amino-... CAS#:42753-75-3 |
| Literature: Erra, Montse; Moreno, Imma; Sanahuja, Jordi; Andres, Miriam; Reinoso, Raquel F.; Lozoya, Estrella; Pizcueta, Pilar; Godessart, Nuria; Castro-Palomino, Julio Cesar Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 24 p. 7268 - 7272 |
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~%
Methyl 5-amino-... CAS#:42753-75-3 |
| Literature: Gattermann Chemische Berichte, 1894 , vol. 27, p. 1930 Full Text Show Details Bayer and Co. Patent: DE79865 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 4, p. 56 |
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~%
Methyl 5-amino-... CAS#:42753-75-3 |
| Literature: Wessely; Benedikt; Benger Monatshefte fuer Chemie, 1949 , vol. 80, p. 197,199 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 8 | |
|---|---|
| DownStream 4 | |
CAS#:22802-67-1
CAS#:104333-09-7![Benzoicacid, 5-[(2-chloroacetyl)amino]-2-hydroxy structure](https://image.chemsrc.com/caspic/353/80074-26-6.png)
CAS#:80074-26-6![methyl 5-[[2-(diethylamino)acetyl]amino]-2-hydroxybenzoate structure](https://image.chemsrc.com/caspic/414/6245-02-9.png)
CAS#:6245-02-9This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2922509090 |
|---|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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[Therapeutic effect of methyl 5-aminosalicylate on experimental ulcerative colitis in rabbits].
Zhongguo Yao Li Xue Bao 11(1) , 54-6, (1990) Using the improved Kirsner model of ulcerative colitis in rabbits, we found that the therapeutic effect of methyl 5-amino salicylate hydrochloride (M-5-AS) was similar to that of sulfasalazine (salicy... |
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[Teratologic studies of methyl 5-aminosalicylate and salicylazopyridine].
Zhongguo Yao Li Xue Bao 13(3) , 265-7, (1992) Methyl 5-aminosalicylate hydrochloride (M-5-AS) at the dosages of 21, 42, 209, and 417 mg.kg-1.d-1 ig to mice during d 6-15 of pregnancy, no obvious effects on the placenta, fetus weight, sex differen... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Benzoic acid, 5-amino-2-hydroxy-, methyl ester |
| MFCD01317557 |
| Benzoic acid, 5-amino-2-hydroxy-, methyl ester (9CI) |
| Methyl 5-amino-2-hydroxybenzoate |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the CAS number of Methyl 5-amino-2-hydroxybenzoate? |
| A: CAS number of Methyl 5-amino-2-hydroxybenzoate is 42753-75-3. |
| Q: What is the English name of Methyl 5-amino-2-hydroxybenzoate? |
| A: The English name of Methyl 5-amino-2-hydroxybenzoate is Methyl 5-amino-2-hydroxybenzoate. |
| Q: What is the InChIKey of Methyl 5-amino-2-hydroxybenzoate? |
| A: InChIKey of Methyl 5-amino-2-hydroxybenzoate is MXUHMQZOATZRIK-UHFFFAOYSA-N. |
| Q: What is the safety information for Methyl 5-amino-2-hydroxybenzoate? |
| A: Safety information for Methyl 5-amino-2-hydroxybenzoate: S26. |
| Q: What are the upstream materials of Methyl 5-amino-2-hydroxybenzoate? |
| A: Related upstream materials(CAS) of Methyl 5-amino-2-hydroxybenzoate: 67-56-1;89-57-6;17302-46-4;89-56-5;7664-93-9;96-97-9;618-95-1;51-78-5. |
| Q: What is the molecular weight of Methyl 5-amino-2-hydroxybenzoate? |
| A: Molecular weight of Methyl 5-amino-2-hydroxybenzoate is 167.162. |
| Q: What is the boiling point of Methyl 5-amino-2-hydroxybenzoate? |
| A: Boiling point of Methyl 5-amino-2-hydroxybenzoate is 319.2±27.0 °C at 760 mmHg. |
| Q: What is the polar surface area (PSA) of Methyl 5-amino-2-hydroxybenzoate? |
| A: Polar surface area (PSA) of Methyl 5-amino-2-hydroxybenzoate is 72.55000. |
| Q: What is the LogP of Methyl 5-amino-2-hydroxybenzoate? |
| A: LogP of Methyl 5-amino-2-hydroxybenzoate is 0.56. |
| Q: What is the SMILES notation of Methyl 5-amino-2-hydroxybenzoate? |
| A: SMILES notation of Methyl 5-amino-2-hydroxybenzoate is COC(=O)c1cc(N)ccc1O. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |