2',3'-Dideoxyuridine structure
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Common Name | 2',3'-Dideoxyuridine | ||
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CAS Number | 5983-09-5 | Molecular Weight | 212.20 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C9H12N2O4 | Melting Point | 127-129 °C(lit.) | |
MSDS | Chinese USA | Flash Point | N/A |
Use of 2',3'-Dideoxyuridine2',3'-Dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
Name | 2',3'-Dideoxyuridine |
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Synonym | More Synonyms |
Description | 2',3'-Dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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Related Catalog | |
References |
Density | 1.3±0.1 g/cm3 |
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Melting Point | 127-129 °C(lit.) |
Molecular Formula | C9H12N2O4 |
Molecular Weight | 212.20 |
Exact Mass | 226.095352 |
PSA | 84.32000 |
LogP | -0.76 |
Index of Refraction | 1.552 |
Storage condition | 2~8°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | C |
Risk Phrases | 34-36/37 |
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2934999090 |
Precursor 6 | |
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DownStream 10 | |
HS Code | 2934999090 |
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Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Abacavir and metabolite pharmacokinetics in HIV-1-infected children and adolescents.
J. Acquir. Immune Defic. Syndr. 51(1) , 54-9, (2009) Abacavir (ABC) oral clearance, adjusted for body size, is approximately 2 times higher for children than adults with a corresponding difference in dose regimens. However, there are limited data availa... |
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Potent DNA chain termination activity and selective inhibition of human immunodeficiency virus reverse transcriptase by 2',3'-dideoxyuridine-5'-triphosphate.
Mol. Pharmacol. 37(2) , 157-63, (1990) 2',3'-Dideoxyuridine (ddUrd) exhibits poor if any anti-human immunodeficiency virus (HIV) activity in ATH8 and MT-4 cells. This is in agreement with the failure of ddUrd to be efficiently anabolized i... |
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Glycosyl-oxycarbonylaminosulfonyl-2',3'-dideoxynucleoside derivatives as lipophilic nucleotide mimics. Synthesis and anti-HIV activity.
Bioorg. Med. Chem. 1(4) , 279-84, (1993) Several lipophilic-2',3'-dideoxynucleotide analogues have been synthesized and tested against Human Immunodeficiency Virus (HIV). Glycosyl-oxycarbonylaminosulfonyl-analogues of 3'-deoxythymidine and 2... |
1-[5-(Hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione |
1-[5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione |
1-[(2R,5S)-5-(Hydroxymethyl)tetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione |
2,4(1H,3H)-Pyrimidinedione, 1-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]- |
2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-[tetrahydro-5-(hydroxymethyl)-2-furanyl]- |
MFCD00013359 |
1-[(2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione |
1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |