(-)-α-Acetylmethadol Hydrochloride
(-)-α-Acetylmethadol Hydrochloride structure
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Common Name | (-)-α-Acetylmethadol Hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 43033-72-3 | Molecular Weight | 389.95900 | |
| Density | N/A | Boiling Point | 456ºC at 760 mmHg | |
| Molecular Formula | C23H32ClNO2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 130ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Summary: (-)-α-Acetylmethadol Hydrochloride, CAS: 43033-72-3, molecular formula: C23H32ClNO2, molecular weight: 389.95900, For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | (-)-α-Acetylmethadol Hydrochloride |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Boiling Point | 456ºC at 760 mmHg |
|---|---|
| Molecular Formula | C23H32ClNO2 |
| Molecular Weight | 389.95900 |
| Flash Point | 130ºC |
| Exact Mass | 389.21200 |
| PSA | 29.54000 |
| LogP | 5.45660 |
| InChIKey | UXBPQRGCVJOTNT-COBSGTNCSA-N |
| SMILES | CCC(OC(C)=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1.Cl |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H300-H315-H319-H335-H413 |
| Precautionary Statements | P261-P264-P301 + P310-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| RIDADR | UN 2811 6.1 / PGII |
| RTECS | MJ3680000 |
| HS Code | 2922199090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~82%
(-)-α-Acetylmet... CAS#:43033-72-3 |
| Literature: Hull, Jonathan D.; Scheinmann, Feodor; Turner, Nicholas J. Tetrahedron Asymmetry, 2003 , vol. 14, # 5 p. 567 - 576 |
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~%
(-)-α-Acetylmet... CAS#:43033-72-3 |
| Literature: Hull, Jonathan D.; Scheinmann, Feodor; Turner, Nicholas J. Tetrahedron Asymmetry, 2003 , vol. 14, # 5 p. 567 - 576 |
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~%
(-)-α-Acetylmet... CAS#:43033-72-3 |
| Literature: Hull, Jonathan D.; Scheinmann, Feodor; Turner, Nicholas J. Tetrahedron Asymmetry, 2003 , vol. 14, # 5 p. 567 - 576 |
|
~%
(-)-α-Acetylmet... CAS#:43033-72-3 |
| Literature: Hull, Jonathan D.; Scheinmann, Feodor; Turner, Nicholas J. Tetrahedron Asymmetry, 2003 , vol. 14, # 5 p. 567 - 576 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 5 | |
|---|---|
| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2922199090 |
|---|---|
| Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Opioids, QTc prolongation, and torsades.
J. Clin. Pharmacol. 52(10) , 1614, (2012)
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Effect of PTSD diagnosis and contingency management procedures on cocaine use in dually cocaine- and opioid-dependent individuals maintained on LAAM: a retrospective analysis.
Am. J. Addict. 19(2) , 169-77, (2010) This randomized clinical trial retrospectively examined the effect of post-traumatic stress disorder (PTSD) and contingency management (CM) on cocaine use in opioid and cocaine dependent individuals m... |
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Sex and opioid maintenance dose influence response to naloxone in opioid-dependent humans: a retrospective analysis.
Pharmacol. Biochem. Behav. 90(4) , 787-96, (2008) Pooled self-report and physiological data from 32 male and 15 female methadone or levo-alpha-acetyl methadol (LAAM) maintained volunteers were retrospectively analyzed for individual differences in re... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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Name: Absorbance-based primary biochemical high throughput screening assay to identify acti...
Source: The Scripps Research Institute Molecular Screening Center
Target: caspase-3 preproprotein [Homo sapiens]
External Id: PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule modulators of NR3A
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: SBCCG-A1015-NR3A-Primary-Assay
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Levomethadyl acetate hydrochloride |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular formula of (-)-α-Acetylmethadol Hydrochloride? |
| A: Molecular formula of (-)-α-Acetylmethadol Hydrochloride is C23H32ClNO2. |
| Q: What is the CAS number of (-)-α-Acetylmethadol Hydrochloride? |
| A: CAS number of (-)-α-Acetylmethadol Hydrochloride is 43033-72-3. |
| Q: What is the InChIKey of (-)-α-Acetylmethadol Hydrochloride? |
| A: InChIKey of (-)-α-Acetylmethadol Hydrochloride is UXBPQRGCVJOTNT-COBSGTNCSA-N. |
| Q: What is the Chinese name of 43033-72-3? |
| A: Chinese name of 43033-72-3 is 43033-72-3. |
| Q: What is the molecular weight of (-)-α-Acetylmethadol Hydrochloride? |
| A: Molecular weight of (-)-α-Acetylmethadol Hydrochloride is 389.95900. |
| Q: What is the boiling point of (-)-α-Acetylmethadol Hydrochloride? |
| A: Boiling point of (-)-α-Acetylmethadol Hydrochloride is 456ºC at 760 mmHg. |
| Q: What is the LogP of (-)-α-Acetylmethadol Hydrochloride? |
| A: LogP of (-)-α-Acetylmethadol Hydrochloride is 5.45660. |
| Q: What is the polar surface area (PSA) of (-)-α-Acetylmethadol Hydrochloride? |
| A: Polar surface area (PSA) of (-)-α-Acetylmethadol Hydrochloride is 29.54000. |
| Q: What is the English name of (-)-α-Acetylmethadol Hydrochloride? |
| A: The English name of (-)-α-Acetylmethadol Hydrochloride is (-)-α-Acetylmethadol Hydrochloride. |
| Q: What are the upstream materials of (-)-α-Acetylmethadol Hydrochloride? |
| A: Related upstream materials(CAS) of (-)-α-Acetylmethadol Hydrochloride: 14019-10-4;75-36-5;86-29-3;7576-08-1;15284-15-8. |