Coumetarol
Modify Date: 2024-01-11 22:16:00
Coumetarol structure
|
Common Name | Coumetarol | ||
|---|---|---|---|---|
| CAS Number | 4366-18-1 | Molecular Weight | 380.34800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H16O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CoumetarolCoumetarol is a vitamin K antagonist. |
| Name | 4-hydroxy-3-[1-(4-hydroxy-2-oxochromen-3-yl)-2-methoxyethyl]chromen-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | Coumetarol is a vitamin K antagonist. |
|---|---|
| Related Catalog | |
| Target |
vitamin K[1] |
| In Vitro | Coumetarol (Dicumoxane), an oral anticoagulant, is active in both models. The vitamin K antagonist Coumetarol is effective in both models after oral treatment but inhibits the thrombus formation more strongly in the arterio-venous shunt model. Treatment with the vitamin K antagonist Coumetarol in a dose of 25 mg/kg p.o. twice daily for 2 days results in a significant reduction in thrombus weight by 50% in the venous stasis model and by 75% in the arterio-venous shunt model. In both experiments the coagulation time as measured by the Thrombotest is prolonged to the same extent[1]. |
| References |
| Molecular Formula | C21H16O7 |
|---|---|
| Molecular Weight | 380.34800 |
| Exact Mass | 380.09000 |
| PSA | 110.11000 |
| LogP | 3.08890 |
| RIDADR | UN 2811 |
|---|---|
| HS Code | 2932209090 |
|
~%
Coumetarol CAS#:4366-18-1 |
| Literature: Veldstra et al. Recueil des Travaux Chimiques des Pays-Bas, 1953 , vol. 72, p. 358,361,364 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Cumetarolo |
| 3,3'-(2-methoxyethane-1,1-diyl)bis(2-hydroxy-4h-chromen-4-one) |
| Cumetharol |
| Cumetarol |
| 4,4'-dihydroxy-3,3'-(2-methoxy-ethane-1,1-diyl)-bis-chromen-2-one |
| 1,1-Bis-(4-hydroxy-2-oxo-2H-chromen-3-yl)-2-methoxy-aethan |
| Cumetarolo [DCIT] |
| 1,1-bis-(4-hydroxy-2-oxo-2H-chromen-3-yl)-2-methoxy-ethane |
| Coumetarolum |
| Coumetarol |
| UNII-UO1VQB3SPZ |