COUMERMYCIN AL structure
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Common Name | COUMERMYCIN AL | ||
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CAS Number | 4434-05-3 | Molecular Weight | 1110.08000 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C55H59N5O20 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of COUMERMYCIN ALCoumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. |
Name | coumermycin A1 |
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Synonym | More Synonyms |
Description | Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. |
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Related Catalog | |
In Vitro | Coumermycin A1-induced-JAK2 signal activation increases the mRNA level of SCOS2, but reducea leptin receptor mRNA level[1]. |
References |
Molecular Formula | C55H59N5O20 |
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Molecular Weight | 1110.08000 |
Exact Mass | 1109.38000 |
PSA | 354.89000 |
LogP | 5.71790 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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Precursor 9 | |
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DownStream 0 |
Multiplexing interactions to control antibiotic release from cyclodextrin hydrogels.
Macromol. Biosci. 11(11) , 1544-52, (2011) A new strategy for affinity-based drug delivery by modification of the drug rather than modification of the device is presented. Rifampin is modified to contain either one or two PEG-adamantane arms, ... |
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Aminocoumarins inhibit osteoclast differentiation and bone resorption via downregulation of nuclear factor of activated T cells c1.
Biochem. Pharmacol. 85(3) , 417-25, (2013) Aminocoumarins, such as coumermycin A1 and novobiocin, are natural products of streptomycetes. They are potent inhibitors of bacterial DNA gyrase and are used to suppress the growth of bacteria in inf... |
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Modulation of chaperone function and cochaperone interaction by novobiocin in the C-terminal domain of Hsp90: evidence that coumarin antibiotics disrupt Hsp90 dimerization.
J. Biol. Chem. 281 , 7161-7171, (2006) The C-terminal domain of Hsp90 displays independent chaperone activity, mediates dimerization, and contains the MEEVD motif essential for interaction with tetratricopeptide repeat-containing immunophi... |
coumamycin |
l)oxy)-4-hydroxy-8-methylcoumarin) |
Sugordomycin D-la |
Coumermycin |
Cumamycin |
coumermycins |
notomycina1 |
COUMERMYCIN A1 |
Notomycin |