2-Isobutoxyethanol

Modify Date: 2025-08-20 10:42:41

2-Isobutoxyethanol Structure
2-Isobutoxyethanol structure
Common Name 2-Isobutoxyethanol
CAS Number 4439-24-1 Molecular Weight 118.174
Density 0.9±0.1 g/cm3 Boiling Point 158.8±8.0 °C at 760 mmHg
Molecular Formula C6H14O2 Melting Point N/A
MSDS N/A Flash Point 50.4±7.7 °C

 Names

Name 2-Isobutoxyethanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 158.8±8.0 °C at 760 mmHg
Molecular Formula C6H14O2
Molecular Weight 118.174
Flash Point 50.4±7.7 °C
Exact Mass 118.099380
PSA 29.46000
LogP 0.61
Vapour Pressure 0.9±0.6 mmHg at 25°C
Index of Refraction 1.416
InChIKey HHAPGMVKBLELOE-UHFFFAOYSA-N
SMILES CC(C)COCCO

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KL3850000
CHEMICAL NAME :
Ethanol, 2-isobutoxy-
CAS REGISTRY NUMBER :
4439-24-1
BEILSTEIN REFERENCE NO. :
1732707
LAST UPDATED :
199712
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C6-H14-O2
MOLECULAR WEIGHT :
118.20
WISWESSER LINE NOTATION :
Q2O1Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 3/4/1969 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1000 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 3/4/1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
652 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 66,368,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
710 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 3/4/1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
8870 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,3940,1982

 Safety Information

RIDADR UN 1993
RTECS KL3850000
HS Code 2909499000

 Synthetic Route

~95%

2-Isobutoxyethanol Structure

2-Isobutoxyethanol

CAS#:4439-24-1

Literature: Vostrikova; Gafarova; Dokichev; Zlotskii Russian Chemical Bulletin, 1999 , vol. 48, # 8 p. 1530 - 1532

~%

2-Isobutoxyethanol Structure

2-Isobutoxyethanol

CAS#:4439-24-1

Literature: Du Pont de Nemours and Co. Patent: US2321608 , 1939 ; Full Text Show Details Du Pont de Nemours and Co. Patent: US2357479 , 1939 ;

~%

2-Isobutoxyethanol Structure

2-Isobutoxyethanol

CAS#:4439-24-1

Literature: Whitesides,G.M. et al. Journal of the American Chemical Society, 1964 , vol. 86, p. 2628 - 2634

~%

2-Isobutoxyethanol Structure

2-Isobutoxyethanol

CAS#:4439-24-1

Literature: Lee, Hyung Soo; Isagawa, Kakuzo; Toyoda, Hiromu; Otsuji, Yoshio Chemistry Letters, 1984 , p. 673 - 676

~1%

2-Isobutoxyethanol Structure

2-Isobutoxyethanol

CAS#:4439-24-1

Detail
Literature: Kirmse, Wolfgang; Jansen, Ulrich Chemische Berichte, 1985 , vol. 118, # 7 p. 2607 - 2625

~%

2-Isobutoxyethanol Structure

2-Isobutoxyethanol

CAS#:4439-24-1

Literature: du Pont de Nemours and Co. Patent: US2321608 , 1939 ; Full Text Show Details du Pont de Nemours and Co. Patent: US2357479 , 1939 ;

 Customs

HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

Ethanol, 2-(2-methylpropoxy)-
Isobutyl cellosolve
EINECS 224-658-5
2-Isobutoxyethanol
Ethylene Glycol Monoisobutyl Ether
2-(2-Methylpropoxy)ethanol
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