Ethyl 1H-indazole-3-carboxylate

Modify Date: 2026-07-01 22:49:59

Ethyl 1H-indazole-3-carboxylate Structure
Ethyl 1H-indazole-3-carboxylate structure
Common Name Ethyl 1H-indazole-3-carboxylate
CAS Number 4498-68-4 Molecular Weight 190.199
Density 1.3±0.1 g/cm3 Boiling Point 353.9±15.0 °C at 760 mmHg
Molecular Formula C10H10N2O2 Melting Point N/A
MSDS N/A Flash Point 167.8±20.4 °C

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 1h-indazole-3-carboxylic acid ethyl ester
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.3±0.1 g/cm3
Boiling Point 353.9±15.0 °C at 760 mmHg
Molecular Formula C10H10N2O2
Molecular Weight 190.199
Flash Point 167.8±20.4 °C
Exact Mass 190.074234
PSA 54.98000
LogP 2.13
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.628
InChIKey YLKPTYMNELPKOL-UHFFFAOYSA-N
SMILES CCOC(=O)c1n[nH]c2ccccc12

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: Ethyl 1h-indazole-3-carboxylate
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:Ethyl 1h-indazole-3-carboxylate
CAS number:4498-68-4

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels, refrigerated.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C10H10N2O2
Molecular weight:190.2

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

HS Code 2933990090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Ethyl 1H-indazole-3-carboxylateBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Name: Absorbance-based primary biochemical high throughput screening assay to identify acti...
Source: The Scripps Research Institute Molecular Screening Center
Target: caspase-3 preproprotein [Homo sapiens]
External Id: PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
Ethyl 1H-indazole-3-carboxylate
MFCD01138134
1H-Indazole-3-carboxylic acid, ethyl ester

 Ethyl 1H-indazole-3-carboxylate | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the InChIKey of 1h-indazole-3-carboxylic acid ethyl ester?
A: InChIKey of 1h-indazole-3-carboxylic acid ethyl ester is YLKPTYMNELPKOL-UHFFFAOYSA-N.
Q: What is the molecular weight of 1h-indazole-3-carboxylic acid ethyl ester?
A: Molecular weight of 1h-indazole-3-carboxylic acid ethyl ester is 190.199.
Q: What English synonyms does 1h-indazole-3-carboxylic acid ethyl ester have?
A: English synonyms of 1h-indazole-3-carboxylic acid ethyl ester: 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER, Ethyl 1H-indazole-3-carboxylate, MFCD01138134, 1H-Indazole-3-carboxylic acid, ethyl ester.
Q: What is the polar surface area (PSA) of 1h-indazole-3-carboxylic acid ethyl ester?
A: Polar surface area (PSA) of 1h-indazole-3-carboxylic acid ethyl ester is 54.98000.
Q: What is the molecular formula of 1h-indazole-3-carboxylic acid ethyl ester?
A: Molecular formula of 1h-indazole-3-carboxylic acid ethyl ester is C10H10N2O2.
Q: What is the LogP of 1h-indazole-3-carboxylic acid ethyl ester?
A: LogP of 1h-indazole-3-carboxylic acid ethyl ester is 2.13.
Q: What is the English name of 1h-indazole-3-carboxylic acid ethyl ester?
A: The English name of 1h-indazole-3-carboxylic acid ethyl ester is 1h-indazole-3-carboxylic acid ethyl ester.
Q: What is the SMILES notation of 1h-indazole-3-carboxylic acid ethyl ester?
A: SMILES notation of 1h-indazole-3-carboxylic acid ethyl ester is CCOC(=O)c1n[nH]c2ccccc12.
Q: What are the downstream products of 1h-indazole-3-carboxylic acid ethyl ester?
A: Related downstream products(CAS) of 1h-indazole-3-carboxylic acid ethyl ester: 34252-44-3;50890-83-0;127472-41-7;1081-04-5;109216-60-6;78155-85-8;865886-78-8;90004-04-9.
Q: What are the upstream materials of 1h-indazole-3-carboxylic acid ethyl ester?
A: Related upstream materials(CAS) of 1h-indazole-3-carboxylic acid ethyl ester: 623-73-4;88284-48-4;186966-08-5;64-17-5;4498-67-3;99-87-6;4492-02-8;62269-48-1;96546-39-3.

 Ethyl 1H-indazole-3-carboxylatefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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