Prostaglandin F2β

Modify Date: 2024-04-02 19:48:40

Prostaglandin F2β Structure
Prostaglandin F2β structure
Common Name Prostaglandin F2β
CAS Number 4510-16-1 Molecular Weight 354.48
Density 1.2±0.1 g/cm3 Boiling Point 531.0±50.0 °C at 760 mmHg
Molecular Formula C20H34O5 Melting Point 105-106ºC
MSDS N/A Flash Point 289.0±26.6 °C

 Use of Prostaglandin F2β


(5R)-Dinoprost is a metabolite produced by cyclooxygenase metabolism of arachidonic acid. (5R)-Dinoprost (Prostaglandin F2β) induces dose-dependent release of hexose containing mucin[1][2].

 Names

Name prostaglandin F2β
Synonym More Synonyms

 Prostaglandin F2β Biological Activity

Description (5R)-Dinoprost is a metabolite produced by cyclooxygenase metabolism of arachidonic acid. (5R)-Dinoprost (Prostaglandin F2β) induces dose-dependent release of hexose containing mucin[1][2].
Related Catalog
References

[1]. Lamont JT, et, al. Cysteamine and prostaglandin F2 beta stimulate rat gastric mucin release. Gastroenterology. 1983 Feb;84(2):306-13.  

[2]. Jang Y, et, al. Molecular mechanisms underlying the actions of arachidonic acid-derived prostaglandins on peripheral nociception. J Neuroinflammation. 2020 Jan 22;17(1):30.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 531.0±50.0 °C at 760 mmHg
Melting Point 105-106ºC
Molecular Formula C20H34O5
Molecular Weight 354.48
Flash Point 289.0±26.6 °C
Exact Mass 354.240631
PSA 97.99000
LogP 2.14
Vapour Pressure 0.0±3.2 mmHg at 25°C
Index of Refraction 1.569

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MJ9658000
CHEMICAL NAME :
5-Heptenoic acid, 7-(3,5-dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)- , stereoisomer
CAS REGISTRY NUMBER :
4510-16-1
LAST UPDATED :
198910
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H34-O5
MOLECULAR WEIGHT :
354.54
WISWESSER LINE NOTATION :
L5TJ AQ B2U4VQ C1U1YQ5 DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
10 mg/kg
SEX/DURATION :
female 19 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - parturition
REFERENCE :
BJPCBM British Journal of Pharmacology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.34- 1968- Volume(issue)/page/year: 36,188P,1969

 Synonyms

Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9β,11α,13E,15S)-
(5Z,9β,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid
9BETA, 11ALPHA-PROSTAGLANDIN F2
prostaglandin F2beta
Prostaglandin F2β