CTB
CTB structure
|
Common Name | CTB | ||
|---|---|---|---|---|
| CAS Number | 451491-47-7 | Molecular Weight | 343.73 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H13ClF3NO2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
Use of CTBCTB (Cholera Toxin B subunit) is a potent p300 histone acetyltransferase activator[1]. CTB can effectively induce apoptosis in MCF-7 cells[2]. |
| Name | CTB |
|---|---|
| Synonym | More Synonyms |
| Description | CTB (Cholera Toxin B subunit) is a potent p300 histone acetyltransferase activator[1]. CTB can effectively induce apoptosis in MCF-7 cells[2]. |
|---|---|
| Related Catalog | |
| Target |
p300 |
| In Vitro | CTB (10, 50, 100, 150, 200, and 250 µM; 10 min) enhances p300 HAT activity of p300 in a dosedependent manner[1]. CTB (0-200 μM; 24 hours) inhibits the viability of MCF-7 cells with an IC50 of 85.43 μM[2]. CTB (85.43 μM; 24, 48 and 72 h) induces time dependence apoptosis of MCF-7 cells[2]. CTB (50 uM; 24 h) increases p300/CBP activity , and reduces autophagic flux in primary neurons[3]. Cell Viability Assay[2] Cell Line: MCF-7 cell Concentration: 0-200 μM Incubation Time: 24 hours Result: Inhibit viability with an IC50 of 85.43 μM. Apoptosis Analysis[2] Cell Line: MCF-7 cell Concentration: 85.43 μM Incubation Time: 24, 48 and 72 h Result: Iinduced time-dependence apoptosis. |
| References |
| Molecular Formula | C16H13ClF3NO2 |
|---|---|
| Molecular Weight | 343.73 |
| Symbol |
GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319-H410 |
| Precautionary Statements | P273-P305 + P351 + P338-P501 |
| Hazard Codes | Xi |
| RIDADR | UN 3077 9 / PGIII |
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| MFCD02356522 |