Methyl 4-amino-2-chlorobenzoate

Modify Date: 2024-01-02 14:45:29

Methyl 4-amino-2-chlorobenzoate Structure
Methyl 4-amino-2-chlorobenzoate structure
Common Name Methyl 4-amino-2-chlorobenzoate
CAS Number 46004-37-9 Molecular Weight 185.608
Density 1.3±0.1 g/cm3 Boiling Point 334.2±22.0 °C at 760 mmHg
Molecular Formula C8H8ClNO2 Melting Point 112-114ºC
MSDS N/A Flash Point 155.9±22.3 °C

 Names

Name Methyl 4-Amino-2-Chlorobenzoate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 334.2±22.0 °C at 760 mmHg
Melting Point 112-114ºC
Molecular Formula C8H8ClNO2
Molecular Weight 185.608
Flash Point 155.9±22.3 °C
Exact Mass 185.024353
PSA 52.32000
LogP 1.98
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.581

 Safety Information

HS Code 2922499990

 Synthetic Route

~99%

Methyl 4-amino-2-chlorobenzoate Structure

Methyl 4-amino-...

CAS#:46004-37-9

Literature: Frantz, Marie-Celine; Rodrigo, Jordi; Boudier, Laure; Durroux, Thierry; Mouillac, Bernard; Hibert, Marcel Journal of Medicinal Chemistry, 2010 , vol. 53, # 4 p. 1546 - 1562

~98%

Methyl 4-amino-2-chlorobenzoate Structure

Methyl 4-amino-...

CAS#:46004-37-9

Literature: NOVARTIS AG; HEBACH, Christina; JOLY, Emilie; KALLEN, Joerg; TERNOIS, James Gilbert; TINTELNOT-BLOMLEY, Marina Patent: WO2013/8162 A1, 2013 ; Location in patent: Page/Page column 116 ;

~60%

Methyl 4-amino-2-chlorobenzoate Structure

Methyl 4-amino-...

CAS#:46004-37-9

Literature: KIRIN BEER KABUSHIKI KAISHA Patent: EP1724268 A1, 2006 ; Location in patent: Page/Page column 86 ;

~95%

Methyl 4-amino-2-chlorobenzoate Structure

Methyl 4-amino-...

CAS#:46004-37-9

Literature: Ferring B.V. Patent: EP1449844 A1, 2004 ; Location in patent: Page 23 ; EP 1449844 A1

~%

Methyl 4-amino-2-chlorobenzoate Structure

Methyl 4-amino-...

CAS#:46004-37-9

Literature: Rubin et al. Journal of the American Chemical Society, 1946 , vol. 68, p. 623

~%

Methyl 4-amino-2-chlorobenzoate Structure

Methyl 4-amino-...

CAS#:46004-37-9

Literature: Kaur, Gurmeet; Narayanan, Ven L.; Risbood, Prabhakar A.; Hollingshead, Melinda G.; Stinson, Sherman F.; Varma, Ravi K.; Sausville, Edward A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1749 - 1761

~%

Methyl 4-amino-2-chlorobenzoate Structure

Methyl 4-amino-...

CAS#:46004-37-9

Literature: GRÜNENTHAL GMBH; FRANK, Robert; CHRISTOPH, Thomas; DAMANN, Nils; LESCH, Bernhard; BAHRENBERG, Gregor; SAUNDERS, Derek John; STOCKHAUSEN, Hannelore; KIM, Yong-Soo; KIM, Myeong-Seop; LEE, Jeewoo Patent: WO2013/68467 A1, 2013 ;

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Synonyms

Benzoic acid, 4-amino-2-chloro-, methyl ester
Methyl 4-amino-2-chlorobenzoate
MFCD03840484
4-Amino-2-Chloro-Benzoic Acid Methyl Ester