2-Chloro-p-aminobenzoic acid

Modify Date: 2024-01-03 00:00:16

2-Chloro-p-aminobenzoic acid Structure
2-Chloro-p-aminobenzoic acid structure
Common Name 2-Chloro-p-aminobenzoic acid
CAS Number 2457-76-3 Molecular Weight 171.581
Density 1.5±0.1 g/cm3 Boiling Point 365.3±27.0 °C at 760 mmHg
Molecular Formula C7H6ClNO2 Melting Point 211 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 174.8±23.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-amino-2-chlorobenzoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 365.3±27.0 °C at 760 mmHg
Melting Point 211 °C (dec.)(lit.)
Molecular Formula C7H6ClNO2
Molecular Weight 171.581
Flash Point 174.8±23.7 °C
Exact Mass 171.008713
PSA 63.32000
LogP 1.26
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.649
Storage condition −20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG1575000
CHEMICAL NAME :
Benzoic acid, 4-amino-2-chloro-
CAS REGISTRY NUMBER :
2457-76-3
BEILSTEIN REFERENCE NO. :
2803668
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H6-Cl-N-O2
MOLECULAR WEIGHT :
171.59
WISWESSER LINE NOTATION :
ZR CG DVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
500 mg/L
REFERENCE :
JGMIAN Journal of General Microbiology. (Soc. for General Microbiology, Journal Sales, 62 London Rd., Reading, RG1 5AS, UK) V.1- 1947- Volume(issue)/page/year: 18,543,1958

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DG1575000
HS Code 29224995

 Synthetic Route

~98%

2-Chloro-p-aminobenzoic acid Structure

2-Chloro-p-amin...

CAS#:2457-76-3

Literature: Gangjee, Aleem; Jain, Hiteshkumar D.; McGuire, John J.; Kisliuk, Roy L. Journal of Medicinal Chemistry, 2004 , vol. 47, # 27 p. 6730 - 6739

~%

2-Chloro-p-aminobenzoic acid Structure

2-Chloro-p-amin...

CAS#:2457-76-3

Literature: Journal of the Indian Chemical Society, , vol. 18, p. 25,26

~%

2-Chloro-p-aminobenzoic acid Structure

2-Chloro-p-amin...

CAS#:2457-76-3

Literature: Chemische Berichte, , vol. 40, p. 3394

~%

2-Chloro-p-aminobenzoic acid Structure

2-Chloro-p-amin...

CAS#:2457-76-3

Literature: Chemische Berichte, , vol. 40, p. 3394

~%

2-Chloro-p-aminobenzoic acid Structure

2-Chloro-p-amin...

CAS#:2457-76-3

Literature: Chemische Berichte, , vol. 40, p. 3394

~%

2-Chloro-p-aminobenzoic acid Structure

2-Chloro-p-amin...

CAS#:2457-76-3

Literature: Chemische Berichte, , vol. 24, p. 706

~%

2-Chloro-p-aminobenzoic acid Structure

2-Chloro-p-amin...

CAS#:2457-76-3

Literature: Chemische Berichte, , vol. 24, p. 706

~%

2-Chloro-p-aminobenzoic acid Structure

2-Chloro-p-amin...

CAS#:2457-76-3

Literature: Chemische Berichte, , vol. 24, p. 706

~%

2-Chloro-p-aminobenzoic acid Structure

2-Chloro-p-amin...

CAS#:2457-76-3

Literature: Journal of the American Chemical Society, , vol. 71, p. 4154

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Articles8

More Articles
Validation of high-performance liquid chromatographic methods on two silica base-deactivated reversed phases for the determination of chloroprocaine and bupivacaine.

J. Pharm. Biomed. Anal. 14(8-10) , 1251-9, (1996)

The separation of HPLC of basic drugs on silica-based reversed phases remains a major problem because of the interaction between the residual silanol groups of the silica and the amino function of the...

Intrapartum paracervical block anesthesia with 2-chloroprocaine.

Am. J. Obstet. Gynecol. 146(1) , 16-22, (1983)

Most of the reports of fetal bradycardia and acidosis following paracervical block anesthesia have involved the use of amide-linked anesthetics, such as lidocaine and mepivacaine. The purposes of this...

Comparison of lidocaine and 2-chloroprocaine in paracervical block: clinical effects and drug concentrations in mother and child.

Anesth. Analg. 62(2) , 168-73, (1983)

2-Chloroprocaine (CP) has recently been recommended as a less toxic alternative to amide-type local anesthetics due to its rapid metabolism. A double-blind, randomized study comparing CP to lidocaine ...

 Synonyms

4-Amino-2-chlorobenzoic acid
Benzoic acid, 4-amino-2-chloro-
EINECS 219-540-5
4-amino-2-chloro-benzoic acid
4-Amino-2-chlor-benzoesaeure
o-Chloro-p-aminobenzoic acid
Benzoic acid,4-amino-2-chloro
2-Chloro-4-aminobenzoic acid
MFCD03407960
2-Chloro-p-aminobenzoic acid
USAF NB-1
Top Suppliers:I want be here




Get all suppliers and price by the below link:

2-Chloro-p-aminobenzoic acid suppliers

2-Chloro-p-aminobenzoic acid price