alpha-Lapachone

Modify Date: 2026-07-02 00:37:36

alpha-Lapachone Structure
alpha-Lapachone structure
Common Name alpha-Lapachone
CAS Number 4707-33-9 Molecular Weight 242.270
Density 1.3±0.1 g/cm3 Boiling Point 372.9±42.0 °C at 760 mmHg
Molecular Formula C15H14O3 Melting Point N/A
MSDS N/A Flash Point 165.5±27.9 °C

 Use of alpha-Lapachone


α-Lapachone shows trypanocidal activity[1].

 Names

Name 2,2-dimethyl-3,4-dihydrobenzo[g]chromene-5,10-dione
Synonym More Synonyms

 alpha-Lapachone Biological Activity

Description α-Lapachone shows trypanocidal activity[1].
Related Catalog
References

[1]. Pinto AV, de Castro SL. The trypanocidal activity of naphthoquinones: a review. Molecules. 2009;14(11):4570-4590. Published 2009 Nov 10.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 372.9±42.0 °C at 760 mmHg
Molecular Formula C15H14O3
Molecular Weight 242.270
Flash Point 165.5±27.9 °C
Exact Mass 242.094299
PSA 43.37000
LogP 3.13
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.595
InChIKey PJWHOPKRRBUSDH-UHFFFAOYSA-N
SMILES CC1(C)CCC2=C(O1)C(=O)c1ccccc1C2=O

 Safety Information

Hazard Codes Xi

 Synthetic Route

 alpha-LapachoneBioassay

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Name: Growth inhibition of human HBL100 cells by SRB assay
Source: ChEMBL
Target: HBL-100
External Id: CHEMBL2038048
Name: Effect on oxygen redox cycling in Trypanosoma cruzi Tulahuen assessed as oxygen consu...
Source: ChEMBL
Target: Trypanosoma cruzi
External Id: CHEMBL921831
Name: Growth inhibition of human WiDr cells by SRB assay
Source: ChEMBL
Target: WiDr
External Id: CHEMBL2038051
Name: Antitrypanosomal activity against Trypanosoma cruzi Tulahuen assessed as trypomastigo...
Source: ChEMBL
Target: Trypanosoma cruzi
External Id: CHEMBL921827
Name: Growth inhibition of human HeLa cells by SRB assay
Source: ChEMBL
Target: HeLa
External Id: CHEMBL2038049
Name: Growth inhibition of human SW1573 cells by SRB assay
Source: ChEMBL
Target: SW1573
External Id: CHEMBL2038050
Name: Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
Source: ChEMBL
Target: MCF7
External Id: CHEMBL1006914
Name: Cytotoxicity against mouse P388 cells after 72 hrs by SRB assay
Source: ChEMBL
Target: P388
External Id: CHEMBL1006913
Name: Cytotoxicity against human Lu1 cells after 72 hrs by SRB assay
Source: ChEMBL
Target: Lu1
External Id: CHEMBL1006916
Name: Cytotoxicity against human LNCAP cells after 72 hrs by SRB assay
Source: ChEMBL
Target: LNCaP
External Id: CHEMBL1006915
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 Synonyms

2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione
α-Lapachone
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