Amino-PEG9-amine

Modify Date: 2024-01-09 18:24:45

Amino-PEG9-amine Structure
Amino-PEG9-amine structure
Common Name Amino-PEG9-amine
CAS Number 474082-35-4 Molecular Weight 456.571
Density 1.1±0.1 g/cm3 Boiling Point 527.4±45.0 °C at 760 mmHg
Molecular Formula C20H44N2O9 Melting Point N/A
MSDS N/A Flash Point 263.9±22.4 °C

 Use of Amino-PEG9-amine


Amino-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3,6,9,12,15,18,21,24,27-Nonaoxanonacosane-1,29-diamine
Synonym More Synonyms

 Amino-PEG9-amine Biological Activity

Description Amino-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 527.4±45.0 °C at 760 mmHg
Molecular Formula C20H44N2O9
Molecular Weight 456.571
Flash Point 263.9±22.4 °C
Exact Mass 456.304688
LogP -4.09
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.467
Storage condition 2-8°C

 Synonyms

3,6,9,12,15,18,21,24,27-Nonaoxanonacosane-1,29-diamine