FAUC-365

Modify Date: 2024-02-28 21:44:37

FAUC-365 Structure
FAUC-365 structure
Common Name FAUC-365
CAS Number 474432-66-1 Molecular Weight 462.435
Density 1.3±0.1 g/cm3 Boiling Point 680.3±55.0 °C at 760 mmHg
Molecular Formula C23H25Cl2N3OS Melting Point N/A
MSDS N/A Flash Point 365.2±31.5 °C

 Use of FAUC-365


FAUC 365 is a highly dopamine D3 receptor-selective antagonist with Ki values of 0.5 nM, 340, 2600, and 3600 nM at D3, D4.4, D2short, and D2Long receptors, respectively. FAUC 365 can be used for the research of schizophrenia, and Parkinson's disease[1][2].

 Names

Name N-{4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl}-1-benzothiophene-2-carboxamide
Synonym More Synonyms

 FAUC-365 Biological Activity

Description FAUC 365 is a highly dopamine D3 receptor-selective antagonist with Ki values of 0.5 nM, 340, 2600, and 3600 nM at D3, D4.4, D2short, and D2Long receptors, respectively. FAUC 365 can be used for the research of schizophrenia, and Parkinson's disease[1][2].
Related Catalog
References

[1]. Philip Seeman, et al. Dopamine D2 and D3 receptors in human putamen, caudate nucleus, and globus pallidus. Synapse. 2006 Sep 1;60(3):205-11.

[2]. Carsten Hocke, et al. Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3963-6.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 680.3±55.0 °C at 760 mmHg
Molecular Formula C23H25Cl2N3OS
Molecular Weight 462.435
Flash Point 365.2±31.5 °C
Exact Mass 461.109528
LogP 7.14
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.638

 Synonyms

N-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl}-1-benzothiophene-2-carboxamide
N-{4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl}-1-benzothiophene-2-carboxamide
Benzo[b]thiophene-2-carboxamide, N-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-
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