cis-ACPD
cis-ACPD structure
|
Common Name | cis-ACPD | ||
|---|---|---|---|---|
| CAS Number | 477331-06-9 | Molecular Weight | 346.333 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H22N2O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of cis-ACPDcis-ACPD is a potent agonist of NMDA receptor, with an IC50 of 3.3 μM. And it is also a selective agonist of group II mGluR, with EC50s of 13 μM and 50 μM for mGluR2 and mGluR4, respectively[1][2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1) |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | cis-ACPD is a potent agonist of NMDA receptor, with an IC50 of 3.3 μM. And it is also a selective agonist of group II mGluR, with EC50s of 13 μM and 50 μM for mGluR2 and mGluR4, respectively[1][2]. |
|---|---|
| Related Catalog | |
| Target |
NMDA:3.3 μM (IC50) mGluR2:13 μM (EC50) mGluR4:50 μM (EC50) |
| In Vitro | cis-ACPD is a selective group II mGluR agonist, with EC50s of 13, 50, >300 and >300 μM for mGluR2, mGluR4, mGluR1 and mGluR5, respectively[2]. cis-ACPD (1-1000 µM; 60 min) stimulates hydrolysis of 3H-phosphoinositide[1]. |
| In Vivo | cis-ACPD (1-1000 mg/kg; i.p.) produces dose-related convulsions in rats[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C14H22N2O8 |
|---|---|
| Molecular Weight | 346.333 |
| Exact Mass | 346.137604 |
| InChIKey | YFYNOWXBIBKGHB-FFWSUHOLSA-N |
| SMILES | NC1(C(=O)O)CCC(C(=O)O)C1 |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid - (1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1) |
| 1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1R,3R)-, compd. with (1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1) |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular formula of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1)? |
| A: Molecular formula of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1) is C14H22N2O8. |
| Q: What English synonyms does (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1) have? |
| A: English synonyms of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1): (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid - (1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1), 1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1R,3R)-, compd. with (1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1). |
| Q: What is the English name of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1)? |
| A: The English name of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1) is (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1). |
| Q: What are the uses of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1)? |
| A: Main uses of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1): cis-ACPD is a potent agonist of NMDA receptor, with an IC50 of 3.3 μM. And it is also a selective agonist of group II mGluR, with EC50s of 13 μM and 50 μM for mGluR2 and mGluR4, respectively[1][2]. |
| Q: What is the InChIKey of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1)? |
| A: InChIKey of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1) is YFYNOWXBIBKGHB-FFWSUHOLSA-N. |
| Q: What is the CAS number of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1)? |
| A: CAS number of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1) is 477331-06-9. |
| Q: What is the molecular weight of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1)? |
| A: Molecular weight of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1) is 346.333. |
| Q: What is the SMILES notation of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1)? |
| A: SMILES notation of (1R,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid-(1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid (1:1) is NC1(C(=O)O)CCC(C(=O)O)C1. |
| Q: What is the Chinese name of 477331-06-9? |
| A: Chinese name of 477331-06-9 is cis-ACPD. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |