Aucubin structure
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Common Name | Aucubin | ||
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CAS Number | 479-98-1 | Molecular Weight | 346.330 | |
Density | 1.6±0.1 g/cm3 | Boiling Point | 669.0±55.0 °C at 760 mmHg | |
Molecular Formula | C15H22O9 | Melting Point | 180 - 184ºC | |
MSDS | Chinese USA | Flash Point | 358.4±31.5 °C |
Use of AucubinAucubin is an iridoid glycoside with a wide range of biological activities, including anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities.IC50 value:Target:In vitro: Aucubin promotes neuronal differentiation and neurite outgrowth in neural stem cells cultured primarily from the rat embryonic hippocampus [1]. Aucubin significantly reversed the elevated gene and protein expression of MMP-3, MMP-9, MMP-13, iNOS, COX-2 and the production of NO induced by IL-1β challenge in rat chondrocytes [2]. In vivo: |
Name | Aucubin |
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Synonym | More Synonyms |
Description | Aucubin is an iridoid glycoside with a wide range of biological activities, including anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities.IC50 value:Target:In vitro: Aucubin promotes neuronal differentiation and neurite outgrowth in neural stem cells cultured primarily from the rat embryonic hippocampus [1]. Aucubin significantly reversed the elevated gene and protein expression of MMP-3, MMP-9, MMP-13, iNOS, COX-2 and the production of NO induced by IL-1β challenge in rat chondrocytes [2]. In vivo: |
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Related Catalog | |
References |
Density | 1.6±0.1 g/cm3 |
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Boiling Point | 669.0±55.0 °C at 760 mmHg |
Melting Point | 180 - 184ºC |
Molecular Formula | C15H22O9 |
Molecular Weight | 346.330 |
Flash Point | 358.4±31.5 °C |
Exact Mass | 346.126373 |
PSA | 149.07000 |
LogP | -3.17 |
Vapour Pressure | 0.0±4.6 mmHg at 25°C |
Index of Refraction | 1.660 |
Storage condition | 2-8°C |
~0% Aucubin CAS#:479-98-1 |
Literature: Cachet, Xavier; Deguin, Brigitte; Koch, Michel; Makhlouf, Kader; Tillequin, Francois Journal of Natural Products, 1999 , vol. 62, # 2 p. 400 - 402 |
~% Aucubin CAS#:479-98-1 |
Literature: Bianco; Passacantilli; Nicoletti; Alves de Lima Tetrahedron, 1982 , vol. 38, # 3 p. 359 - 362 |
~% Aucubin CAS#:479-98-1 |
Literature: Bianco; Passacantilli; Nicoletti; Alves de Lima Tetrahedron, 1982 , vol. 38, # 3 p. 359 - 362 |
~% Aucubin CAS#:479-98-1 |
Literature: Bianco; Passacantilli; Nicoletti; Alves de Lima Tetrahedron, 1982 , vol. 38, # 3 p. 359 - 362 |
~% Aucubin CAS#:479-98-1 |
Literature: Weinges, Klaus; Ziegler, Hans Juergen Liebigs Annalen der Chemie, 1990 , # 7 p. 715 - 717 |
Precursor 2 | |
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Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance.
Biol. Pharm. Bull. 37(8) , 1383-9, (2014) In the present study, we examined the interaction of antimicrobial agents with four model lipid membranes that mimicked mammalian cell membranes and Gram-positive and -negative bacterial membranes and... |
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Positive cooperativity between acceptor and donor sites of the peptidoglycan glycosyltransferase.
Biochem. Pharmacol. 93(2) , 141-50, (2015) The glycosyltransferases of family 51 (GT51) catalyze the polymerization of lipid II to form linear glycan chains, which, after cross linking by the transpeptidases, form the net-like peptidoglycan ma... |
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Investigation of the interactions between the EphB2 receptor and SNEW peptide variants.
Growth Factors 32(6) , 236-46, (2014) EphB2 interacts with cell surface-bound ephrin ligands to relay bidirectional signals. Overexpression of the EphB2 receptor protein has been linked to different types of cancer. The SNEW (SNEWIQPRLPQH... |
Rhimanthin |
EINECS 207-540-8 |
Aucubin |
Rhinanthin |
(2S,3R,4S,5S,6R)-2-{[(1S,4aR,5S,7aS)-5-Hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl]oxy}-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol |
Rhimantin |
(1S,4aR,5S,7aS)-5-Hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl β-D-glucopyranoside |
β-D-Glucopyranoside, (1S,4aR,5S,7aS)-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl |
AUCUBOSIDE |
[1S-(1a,4aa,5a,7a)]-1,4a,5,7a-Tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl-b-D-glucopyranoside |
MFCD00136026 |
(2S,3R,4S,5S,6R)-2-{[(1S,4aR,5S,7aS)-5-Hydroxy-7-(hydroxyméthyl)-1,4a,5,7a-tétrahydrocyclopenta[c]pyran-1-yl]oxy}-6-(hydroxyméthyl)tétrahydro-2H-pyran-3,4,5-triol |
(2S,3R,4S,5S,6R)-2-{[(1S,4aR,5S,7aS)-5-Hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyr-1-yl]oxy}-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol |
(1S,4aR,5S,7aS)-5-Hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyr-1-yl-β-D-glucopyranoside |