Amino-PEG11-amine
Modify Date: 2024-01-18 16:07:08
Amino-PEG11-amine structure
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Common Name | Amino-PEG11-amine | ||
|---|---|---|---|---|
| CAS Number | 479200-82-3 | Molecular Weight | 544.677 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 591.2±45.0 °C at 760 mmHg | |
| Molecular Formula | C24H52N2O11 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 299.9±22.4 °C | |
Use of Amino-PEG11-amineAmino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer[1]. |
| Name | 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diamine |
|---|---|
| Synonym | More Synonyms |
| Description | Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 591.2±45.0 °C at 760 mmHg |
| Molecular Formula | C24H52N2O11 |
| Molecular Weight | 544.677 |
| Flash Point | 299.9±22.4 °C |
| Exact Mass | 544.357117 |
| LogP | -4.81 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.468 |
| Storage condition | 2-8°C |
| 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diamine |