Cotinine
Cotinine structure
|
Common Name | Cotinine | ||
|---|---|---|---|---|
| CAS Number | 486-56-6 | Molecular Weight | 176.215 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 316.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C10H12N2O | Melting Point | 40-42ºC | |
| MSDS | Chinese USA | Flash Point | 166.7±25.9 °C | |
| Symbol |
GHS02, GHS06, GHS08 |
Signal Word | Danger | |
Use of CotinineCotinine is an alkaloid found in tobacco and is also the predominant metabolite of nicotine, used as a biomarker for exposure to tobacco smoke. |
| Name | (-)-cotinine |
|---|---|
| Synonym | More Synonyms |
| Description | Cotinine is an alkaloid found in tobacco and is also the predominant metabolite of nicotine, used as a biomarker for exposure to tobacco smoke. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 316.0±0.0 °C at 760 mmHg |
| Melting Point | 40-42ºC |
| Molecular Formula | C10H12N2O |
| Molecular Weight | 176.215 |
| Flash Point | 166.7±25.9 °C |
| Exact Mass | 176.094955 |
| PSA | 33.20000 |
| LogP | -0.23 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.556 |
| Storage condition | 2-8°C |
| Stability | Stable. Incompatible with strong oxidizing agents. May be heat sensitive - store cold. |
| Water Solubility | Not miscible or difficult to mix in water. Soluble in dimethyl sulfoxide (100 mM), ethanol (50 mg/ml, yielding a clear, faint yellow to yellow solution), methanol and chloroform. |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS02, GHS06, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H301 + H311 + H331-H370 |
| Precautionary Statements | P210-P260-P280-P301 + P310-P311 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful;Xi: Irritant; |
| Risk Phrases | R22 |
| Safety Phrases | S36/37 |
| RIDADR | UN 1230 3/PG 2 |
| WGK Germany | 3 |
| RTECS | GN1925500 |
| HS Code | 2933990090 |
|
~44%
Cotinine CAS#:486-56-6 |
| Literature: Synlett, , # 9 p. 1413 - 1416 |
|
~%
Cotinine CAS#:486-56-6 |
| Literature: Journal of Medicinal Chemistry, , vol. 23, # 8 p. 960 - 962 |
|
~50%
Cotinine CAS#:486-56-6 |
| Literature: Pharmazie, , vol. 64, # 4 p. 219 - 226 |
|
~28%
Cotinine CAS#:486-56-6
Detail
|
| Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 42, # 4 p. 387 - 407 |
|
~%
Cotinine CAS#:486-56-6 |
| Literature: Journal of the American Chemical Society, , vol. 81, p. 3951,3954 |
|
~%
Cotinine CAS#:486-56-6 |
| Literature: Archives of Biochemistry, , vol. 79, p. 124,127 |
| Precursor 4 | |
|---|---|
| DownStream 7 | |
CAS#:34834-67-8
CAS#:37096-14-3
CAS#:36508-80-2
CAS#:3000-74-6![3-[(2S)-1-methyl-3,4-dihydro-2H-pyrrol-1-ium-2-yl]pyridine,perchloric acid,perchlorate structure](https://image.chemsrc.com/caspic/224/71014-67-0.png)
CAS#:71014-67-0| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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| (S)-Cotinine |
| (5S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone |
| (5S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-on |
| T6NJ C- ET5NVTJ A1 &&S Form |
| L-COTININE |
| cotinine |
| (S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone |
| (S)-1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one |
| (-)-Cotinine,(S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone |
| (−)-Cotinine |
| 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (5S)- |
| (S)-1-Methyl-5-(3-pyridyl)-2-pyrrolidinone |
| (-)-Cotinine |
| S-(-)-Cotinine |
| MFCD00077696 |
| (S)-N-Methyl-2-(3-pyridyl)-5-pyrrolidone |
| Bifemelane hydrochloride |
| EINECS 207-634-9 |
| CREATINE ETHYL ESTER ANALYSIS KIT |