Bufotenine

Modify Date: 2026-07-05 16:57:50

Bufotenine structure	Common Name	Bufotenine
	CAS Number	487-93-4	Molecular Weight	204.26800
	Density	1.178g/cm3	Boiling Point	392.8ºC at 760 mmHg
	Molecular Formula	C₁₂H₁₆N₂O	Melting Point	62-64ºC
	MSDS	N/A	Flash Point	191.3ºC
	Symbol	GHS02, GHS07	Signal Word	Danger

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	bufotenin
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.178g/cm3
Boiling Point	392.8ºC at 760 mmHg
Melting Point	62-64ºC
Molecular Formula	C₁₂H₁₆N₂O
Molecular Weight	204.26800
Flash Point	191.3ºC
Exact Mass	204.12600
PSA	39.26000
LogP	1.97760
Vapour Pressure	9.89E-07mmHg at 25°C
Index of Refraction	1.646
InChIKey	VTTONGPRPXSUTJ-UHFFFAOYSA-N
SMILES	CN(C)CCc1c[nH]c2ccc(O)cc12
Storage condition	Refrigerator, Under Inert Atmosphere

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NM2800000

CHEMICAL NAME :: Indol-5-ol, 3-(2-(dimethylamino)ethyl)-

CAS REGISTRY NUMBER :: 487-93-4

BEILSTEIN REFERENCE NO. :: 0160628

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C12-H16-N2-O

MOLECULAR WEIGHT :: 204.30

WISWESSER LINE NOTATION :: T56 BMJ D2N1&1 GQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Human

DOSE/DURATION :: 57 ug/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - sensory change involving peripheral nerve Lungs, Thorax, or Respiration - other changes Gastrointestinal - other changes

REFERENCE :: SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 123,886,1956

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 290 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 16,385,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 64,144,1968

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Cardiac - other changes

REFERENCE :: AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 86,138,1920

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS02, GHS07
Signal Word	Danger
Hazard Statements	H225-H302 + H312 + H332-H319
Precautionary Statements	P210-P280-P305 + P351 + P338
Hazard Codes	F,Xn
Risk Phrases	11-20/21/22-36
Safety Phrases	16-36/37
RIDADR	UN 1544
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2933990090

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 9
CAS#:1019-45-0 5-Methoxydimeth... CAS#:24424-99-5 Di-tert-butyl d... CAS#:53157-48-5 N-tert-Butyloxy... CAS#:25390-67-4 N,N-Dimethyl-5-...
CAS#:161202-91-1 1-hydroxy-N,N-d... CAS#:64656-15-1 (2S,3R,4S,5S,6R... CAS#:66521-34-4 N,N-dimethyl-2-... CAS#:61-50-7 Dimethyltryptamine
CAS#:38662-17-8 2-(indolin-3-yl...
DownStream 3
CAS#:1019-44-9 2-(5-hydroxy-1H... CAS#:487-91-2 bufotenidine CAS#:5787-02-0 Bufotenine meth...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

Psychedelic 5-methoxy-N,N-dimethyltryptamine: metabolism, pharmacokinetics, drug interactions, and pharmacological actions.

Curr. Drug Metab. 11(8) , 659-66, (2010)

5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) belongs to a group of naturally-occurring psychoactive indolealkylamine drugs. It acts as a nonselective serotonin (5-HT) agonist and causes many physiolog...

Isolation of N,N-dimethyl and N-methylserotonin 5-O-β-glucosides from immature Zanthoxylum piperitum seeds.

Biosci. Biotechnol. Biochem. 74(9) , 1951-2, (2010)

Two serotonin derivatives, N,N-dimethylserotonin 5-O-β-glucoside (1a) and N-methylserotonin 5-O-β-glucoside (1b) were isolated from immature seeds of Zanthoxylum piperitum. Their structures were deter...

A critical review of reports of endogenous psychedelic N, N-dimethyltryptamines in humans: 1955-2010.

Drug Test. Anal. 4(7-8) , 617-35, (2012)

Three indole alkaloids that possess differing degrees of psychotropic/psychedelic activity have been reported as endogenous substances in humans; N,N-dimethyltryptamine (DMT), 5-hydroxy-DMT (bufotenin...

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Evaluated for the binding affinity to hippocampus striatal membranes at 5-hydroxytryp...
Source: ChEMBL
Target: 5-hydroxytryptamine receptor 1A
External Id: CHEMBL615963

Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: Binding affinity at rat 5-hydroxytryptamine 7 receptor.
Source: ChEMBL
Target: 5-hydroxytryptamine receptor 7
External Id: CHEMBL620766

Name: Agonistic activity against rat 5-HT7 adenyl cyclase expressed in HEK293 cells; Active
Source: ChEMBL
Target: 5-hydroxytryptamine receptor 7
External Id: CHEMBL619703

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Total 267, Current Page 1 of 27

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Bufotenin

Cohoba

Mapine

Mappine

Mappin

Bufotenine

N,N-Dimethylserotonin

EINECS 207-667-9

3-[2-(dimethylamino)ethyl]-1H-indol-5-ol

Dimethylserotonin

5-hydroxy-N,N-dimethyltryptamine

N,N-Dimethyl-5-hydroxytryptamine

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the upstream materials of bufotenin?

A: Related upstream materials(CAS) of bufotenin: 1019-45-0;24424-99-5;53157-48-5;25390-67-4;161202-91-1;64656-15-1;66521-34-4;61-50-7;38662-17-8.

Q: What is the English name of bufotenin?

A: The English name of bufotenin is bufotenin.

Q: What is the molecular weight of bufotenin?

A: Molecular weight of bufotenin is 204.26800.

Q: What is the CAS number of bufotenin?

A: CAS number of bufotenin is 487-93-4.

Q: What English synonyms does bufotenin have?

A: English synonyms of bufotenin: Bufotenin, Cohoba, Mapine, Mappine, Mappin, Bufotenine, N,N-Dimethylserotonin, EINECS 207-667-9, 3-[2-(dimethylamino)ethyl]-1H-indol-5-ol, Dimethylserotonin, 5-hydroxy-N,N-dimethyltryptamine, N,N-Dimethyl-5-hydroxytryptamine.

Q: What is the InChIKey of bufotenin?

A: InChIKey of bufotenin is VTTONGPRPXSUTJ-UHFFFAOYSA-N.

Q: What is the molecular formula of bufotenin?

A: Molecular formula of bufotenin is C12H16N2O.

Q: What is the melting point of bufotenin?

A: Melting point of bufotenin is 62-64ºC.

Q: What is the LogP of bufotenin?

A: LogP of bufotenin is 1.97760.

Q: What is the safety information for bufotenin?

A: Safety information for bufotenin: 16-36/37.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Bufotenine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

naturewill
China
Product Name: Bufotenine
Price: ￥Inquiry/5mg ￥Inquiry/20mg ￥Inquiry/100mg ￥Inquiry/1g
Purity: 98.0%
Delivery: Inquiry
Contact: Bella
Email: 3157321941@qq.com

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