Lutidinic acid

Modify Date: 2024-01-02 13:16:24

Lutidinic acid structure	Common Name	Lutidinic acid
	CAS Number	499-80-9	Molecular Weight	167.12
	Density	1.6±0.1 g/cm3	Boiling Point	574.8±35.0 °C at 760 mmHg
	Molecular Formula	C₇H₅NO₄	Melting Point	243-246 °C
	MSDS	N/A	Flash Point	301.4±25.9 °C

Use of Lutidinic acid

2,4-PDCA (2,4 pyridine dicarboxylic acid) is a broad-spectrum inhibitor of 2OG oxygenase, including JmjC domain-containing family of histone demethylases (JHDMs). 2,4-PDCA is a target chemical in the field of bio-based plastics[1][2][3].

Name	lutidinic acid
Synonym	More Synonyms

Description	2,4-PDCA (2,4 pyridine dicarboxylic acid) is a broad-spectrum inhibitor of 2OG oxygenase, including JmjC domain-containing family of histone demethylases (JHDMs). 2,4-PDCA is a target chemical in the field of bio-based plastics[1][2][3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Demethylase
References	[1]. Brewitz L, et al. Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases. J Fluor Chem. 2021 Jul;247:109804. [2]. Gómez-Álvarez H, et al. Bioconversion of lignin-derived aromatics into the building block pyridine 2,4-dicarboxylic acid by engineering recombinant Pseudomonas putida strains. Bioresour Technol. 2022 Feb;346:126638. [3]. Brewitz L, et al. Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases. J Fluor Chem. 2021 Jul;247:109804.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> Histone Demethylase

References

[1]. Brewitz L, et al. Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases. J Fluor Chem. 2021 Jul;247:109804.

[2]. Gómez-Álvarez H, et al. Bioconversion of lignin-derived aromatics into the building block pyridine 2,4-dicarboxylic acid by engineering recombinant Pseudomonas putida strains. Bioresour Technol. 2022 Feb;346:126638.

[3]. Brewitz L, et al. Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases. J Fluor Chem. 2021 Jul;247:109804.

Density	1.6±0.1 g/cm3
Boiling Point	574.8±35.0 °C at 760 mmHg
Melting Point	243-246 °C
Molecular Formula	C₇H₅NO₄
Molecular Weight	167.12
Flash Point	301.4±25.9 °C
Exact Mass	167.021851
PSA	87.49000
LogP	-0.19
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.628

Lutidinic acid MSDS(Chinese)

Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S24/25
HS Code	29333999

2,4-Lutidine

CAS#:108-47-4

~50%

Lutidinic acid

CAS#:499-80-9

Literature: Iovel', I. G.; Gol'dberg, Yu. Sh.; Gaukhman, A. P.; Zolotoyabko, R. M.; Shimanskaya, M. V. Chemistry of Heterocyclic Compounds (New York, NY, United States), 1991 , vol. 27, # 7 p. 768 - 771 Khimiya Geterotsiklicheskikh Soedinenii, 1991 , # 7 p. 959 - 962

2-Pyridinecarbo...

CAS#:54089-05-3

Lutidinic acid

CAS#:499-80-9

Literature: Lonza Ltd. Patent: US5614636 A1, 1997 ;

2-ethyl-4-methy...

CAS#:2150-18-7

Lutidinic acid

CAS#:499-80-9

Literature: Eckert; Loria Monatshefte fuer Chemie, 1917 , vol. 38, p. 239

4-ETHYL-2-METHY...

CAS#:536-88-9

Lutidinic acid

CAS#:499-80-9

Literature: Eckert; Loria Monatshefte fuer Chemie, 1917 , vol. 38, p. 239

2,4-Lutidine

CAS#:108-47-4

Sulfuric acid

CAS#:7664-93-9

2-Methylisonico...

CAS#:4021-11-8

Lutidinic acid

CAS#:499-80-9

Literature: Ochiai; Okuda Yakugaku Zasshi, 1950 , vol. 70, p. 156,159 Chem.Abstr., 1950 , p. 5878

Precursor 4
CAS#:108-47-4 2,4-Lutidine CAS#:2150-18-7 2-ethyl-4-methy... CAS#:536-88-9 4-ETHYL-2-METHY... CAS#:7664-93-9 Sulfuric acid
DownStream 10
CAS#:41438-38-4 Diethyl 2,4-pyr... CAS#:20857-17-4 Ethanone, 1,1-(... CAS#:25658-36-0 2,4-Pyridinedic... CAS#:24195-10-6 2-(Methoxycarbo...
CAS#:100-48-1 Isonicotinonitrile CAS#:110-86-1 Pyridine CAS#:55-22-1 Isonicotinic acid CAS#:124-38-9 Carbon dioxide
CAS#:1453-82-3 Isonicotinamide CAS#:128075-79-6 LUFIRONIL

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2,4-Pyridinedicarboxylic acid

EINECS 207-892-2

MFCD00006296

2,4-Lutidinic Acid

Pyridine-2,4-dicarboxylic acid

Lutidinic acid

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Lutidinic acid
Price: ￥88.0/1g ￥188.0/5g
Purity: 95.0%
Stocking Period: Inquiry
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,4-Pyridinedicarboxylic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: lutidinic acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Lutidinic acid

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