Hydrocortisone cypionate
Modify Date: 2024-01-02 21:54:39
Hydrocortisone cypionate structure
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Common Name | Hydrocortisone cypionate | ||
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| CAS Number | 508-99-6 | Molecular Weight | 486.64000 | |
| Density | 1.22g/cm3 | Boiling Point | 645ºC at 760mmHg | |
| Molecular Formula | C29H42O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 208.4ºC | |
Use of Hydrocortisone cypionateHydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. |
| Name | 17-Hydroxycorticosterone 21.β.-cyclopentylpropionate |
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| Synonym | More Synonyms |
| Description | Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. |
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| Related Catalog | |
| In Vitro | Hydrocortisone (50 nM) shows a dose-dependent down-regulation of GR transcript in hCMEC/D3 cells. Hydrocortisone supplementation of the serum-reduced cell differentiation medium leads to a significant increase in TER across the hCMEC/D3 monolayer[1]. Hydrocortisone-treated Dendritic cells (DCs) show a decreased expression of MHC II molecules, the costimulatory molecule CD86, and the DC-specific marker CD83, as well as a strongly reduced IL-12 secretion. Hydrocortisone-treated DCs inhibit production of IFN-γ but induce an increased release of IL-4 and no change in IL-5[2]. Hydrocortisone reduces postischemic oxidative stress, perfusion pressure, and transudate formation. Hydrocortisone inhibits postischemic shedding of syndecan-1, heparan sulfate, and hyaluronan as is release of histamine from resident mast cells[3]. |
| References |
| Density | 1.22g/cm3 |
|---|---|
| Boiling Point | 645ºC at 760mmHg |
| Molecular Formula | C29H42O6 |
| Molecular Weight | 486.64000 |
| Flash Point | 208.4ºC |
| Exact Mass | 486.29800 |
| PSA | 100.90000 |
| LogP | 4.30290 |
| Index of Refraction | 1.572 |
| Storage condition | 2-8℃ |
| RIDADR | NONH for all modes of transport |
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| Hydrocortisone cypionate |