Neostigmine Methylsulfate structure
|
Common Name | Neostigmine Methylsulfate | ||
---|---|---|---|---|
CAS Number | 51-60-5 | Molecular Weight | 334.389 | |
Density | N/A | Boiling Point | 457ºC | |
Molecular Formula | C13H22N2O6S | Melting Point | 175-177 °C(lit.) | |
MSDS | Chinese USA | Flash Point | N/A | |
Symbol |
GHS06, GHS08 |
Signal Word | Danger |
Use of Neostigmine MethylsulfateNeostigmine methyl sulfate is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier. |
Name | 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate |
---|---|
Synonym | More Synonyms |
Description | Neostigmine methyl sulfate is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier. |
---|---|
Related Catalog |
Boiling Point | 457ºC |
---|---|
Melting Point | 175-177 °C(lit.) |
Molecular Formula | C13H22N2O6S |
Molecular Weight | 334.389 |
Exact Mass | 334.119843 |
PSA | 104.35000 |
LogP | 2.11750 |
Water Solubility | 1g/10mL |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Symbol |
GHS06, GHS08 |
---|---|
Signal Word | Danger |
Hazard Statements | H300-H315-H319-H334-H335 |
Precautionary Statements | Missing Phrase - N15.00950417-P261-P284-P304 + P340-P305 + P351 + P338-P342 + P311 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
Hazard Codes | T+: Very toxic; |
Risk Phrases | R26/27/28;R36/37/38;R42/43 |
Safety Phrases | S36-S45-S36/37/39-S28A |
RIDADR | UN 2811 6.1/PG 2 |
WGK Germany | 3 |
RTECS | CY1225000 |
Packaging Group | II |
Hazard Class | 6.1(a) |
HS Code | 2924299090 |
~83% Neostigmine Met... CAS#:51-60-5 |
Literature: NEON LABORATORIES LTD.; DALVI, Mahesh Bhagoji; KENNY, Rajesh Shashikant; TARADE, Pradeep Kisan; CHINCHKAR, Dattatray Krishna Patent: WO2012/131699 A1, 2012 ; Location in patent: Page/Page column 15 ; |
~% Neostigmine Met... CAS#:51-60-5 |
Literature: Hoffmann-La Roche Patent: CH208883 , 1938 ; |
Precursor 3 | |
---|---|
DownStream 0 |
HS Code | 2924299090 |
---|---|
Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Chiral analysis of bambuterol, its intermediate and active drug in human plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 997 , 38-44, (2015) A sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed for simultaneous chiral analysis of an antiasthma drug bambuterol, its key intermediate monocarbamate ba... |
|
Simultaneous determination of bambuterol and its two major metabolites in human plasma by hydrophilic interaction ultra-performance liquid chromatography-tandem mass spectrometry.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 225-34, (2014) In this study, a rapid and sensitive hydrophilic interaction ultra-performance liquid chromatography-tandem mass spectrometry (HILIC-UPLC-MS/MS) method was developed for simultaneous determination of ... |
|
In vivo and in vitro effects of neostigmine on gastrointestinal tract motility of horses.
Am. J. Vet. Res. 74(4) , 579-88, (2013) To determine the response to neostigmine of the contractile activity of the jejunum and pelvic flexure and the effects of a continuous rate infusion (CRI) of neostigmine in horses.7 adult horses and t... |
proserin |
Normastigmin |
prostigmine |
neostigmeth |
Stiglyn |
MFCD00011795 |
3-(N,N-Dimethylcarbamoyloxy)-N,N,N,-trimethylanilinium methyl sulfate |
(3-Hydroxyphenyl)trimethylammonium Methyl Sulfate Dimethylcarbamate |
neostigmine methyl sulphate |
polstigmine |
Neostygmine methyl sulfate |
NeostigMine Methyl Sulfate |
hodostin |
tl-1394 |
EINECS 200-109-5 |
Prostigmin |
(3-Dimethylcarbamoyloxyphenyl)trimethylammonium Methyl Sulfate |
GD-65 |
Neostigmine Methylsulfate |
[3-(Dimethylcarbamoxy)phenyl]trimethylammonium methyl sulfate |
Carbamic acid, N,N-dimethyl-, 3-(trimethylammonio)phenyl ester, methyl sulfate |
ar-32 |
3-[(Dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium methyl sulfate |
Intrastigmina |
neostigmine methylsulphate |
3-((Dimethylcarbamoyl)oxy)-N,N,N-trimethylbenzenaminium methyl sulfate |
[3-(Dimethylcarbamoyl)oxyphenyl]trimethylammonium methyl sulfate |
Ammonium, [3-(dimethylcarbamoyloxy)phenyl]trimethyl-, methyl sulfate |
sb-23 |
Neostigmine (methyl sulfate) |