Taraxerone

Modify Date: 2025-08-25 11:03:57

Taraxerone structure	Common Name	Taraxerone
	CAS Number	514-07-8	Molecular Weight	424.702
	Density	1.0±0.1 g/cm3	Boiling Point	488.3±44.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₄₈O	Melting Point	N/A
	MSDS	N/A	Flash Point	202.8±23.4 °C

Use of Taraxerone

Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively[1].

Name	Taraxerone
Synonym	More Synonyms

Description	Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Aldehyde Dehydrogenase (ALDH) Research Areas >> Inflammation/Immunology
Target	EC50: 512.42 μM (ADH); 500.16 μM (ALDH)[1]
In Vivo	Taraxerone significantly lowers the plasma alcohol and acetaldehyde concentrations in mice. Compare to the control group, the ADH and ALDH expressions in the liver tissues are abruptly increased in the taraxerone-treated groups after ethanol exposure[1]. Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration[1].
References	[1]. Sung CK, et al. Taraxerone enhances alcohol oxidation via increases of alcohol dehyderogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities and gene expressions.Food Chem Toxicol. 2012 Jul;50(7):2508-14.

Density	1.0±0.1 g/cm3
Boiling Point	488.3±44.0 °C at 760 mmHg
Molecular Formula	C₃₀H₄₈O
Molecular Weight	424.702
Flash Point	202.8±23.4 °C
Exact Mass	424.370514
PSA	17.07000
LogP	10.48
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.534
InChIKey	DBCAVZSSFGIHQZ-YLAYQGCQSA-N
SMILES	CC1(C)CCC2(C)CC=C3C(C)(CCC4C3(C)CCC3C(C)(C)C(=O)CCC34C)C2C1

Hazard Codes	Xi

Name: Antiproliferative activity against human KB cells after 72 hrs by SRB assay
Source: ChEMBL
Target: KB
External Id: CHEMBL4150961

Name: Antiproliferative activity against human KBVIN cells after 72 hrs by SRB assay
Source: ChEMBL
Target: N/A
External Id: CHEMBL4150962

Name: Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cells
Source: ChEMBL
Target: Nitric oxide synthase, inducible
External Id: CHEMBL942189

Name: Antiproliferative activity against human A549 cells after 72 hrs by SRB assay
Source: ChEMBL
Target: A549
External Id: CHEMBL4150958

Name: Inhibition of NADPH oxidase in LPS-induced mouse BV2 cells assessed as NOX-dependent ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL942188

Name: Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by SRB assay
Source: ChEMBL
Target: MDA-MB-231
External Id: CHEMBL4150959

Name: Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay
Source: ChEMBL
Target: MCF7
External Id: CHEMBL4150960

Name: Antiparasitic activity against Trypanosoma brucei rhodesiense STIB 900 bloodstream fo...
Source: ChEMBL
Target: Trypanosoma brucei rhodesiense
External Id: CHEMBL1776447

Name: Antiplasmodial activity against chloroquine- and pyrimethamine-resistant Plasmodium f...
Source: ChEMBL
Target: Plasmodium falciparum
External Id: CHEMBL1776446

Name: Cytotoxicity against rat L6 cells after 72 hrs by microplate fluorimetry
Source: ChEMBL
Target: L6
External Id: CHEMBL1776448

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(4aR,6aR,8aR,12aR,12bS,14aR,14bR)-4,4,6a,8a,11,11,12b,14b-Octamethyl-1,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-octadecahydro-3(2H)-picenone

(4aR,6aR,8aR,12aR,12bS,14aR,14bR)-4,4,6a,8a,11,11,12b,14b-octamethyl-1,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-octadecahydropicen-3(2H)-one

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China
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China
Product Name: Taraxerone
Price: ￥2400.0/5mg
Purity: 98.0%
Delivery: 3 Day
Contact: Liu jia
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