N-Boc-1,5-diaminopentane

Modify Date: 2024-01-02 19:37:54

N-Boc-1,5-diaminopentane Structure
N-Boc-1,5-diaminopentane structure
 Common Name N-Boc-1,5-diaminopentane
CAS Number 51644-96-3 Molecular Weight 202.294
Density 1.0±0.1 g/cm3 Boiling Point 309.2±25.0 °C at 760 mmHg
Molecular Formula C10H22N2O2 Melting Point N/A
MSDS Chinese USA Flash Point 140.8±23.2 °C
Symbol GHS05
GHS05		 Signal Word Danger

 Use of N-Boc-1,5-diaminopentane


PROTAC Linker 23 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 23 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name N-(5-Aminoamyl)Carbamic Acid Tert-Butyl Ester
Synonym More Synonyms

 N-Boc-1,5-diaminopentane Biological Activity

Description PROTAC Linker 23 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 23 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl-Chain
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 309.2±25.0 °C at 760 mmHg
Molecular Formula C10H22N2O2
Molecular Weight 202.294
Flash Point 140.8±23.2 °C
Exact Mass 202.168121
PSA 64.35000
LogP 1.29
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.458
Storage condition 2-8°C

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C: Corrosive;
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 2735 8/PG 3
WGK Germany 3
HS Code 2924199090

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles3

More Articles
Structure-activity relationships among methoctramine-related polymethylene tetraamines. Chain-length and substituent effects on M-2 muscarinic receptor blocking activity.

J. Med. Chem. 32 , 79, (1989)

Several polymethylene tetraamines related to methoctramine (1) were prepared and evaluated for their blocking activity on M-2 muscarinic receptors in guinea pig atria and ileum. It turned out that ant...
T. Teshima et al.

Tetrahedron 47 , 3305, (1991)
V.J. Jasys et al.

J. Org. Chem. 57 , 1814, (1992)

 Synonyms

N-Boc-cadaverine
N-(5-Aminopentyl)carbamic Acid tert-Butyl Ester
tert-Butyl (5-aminopentyl)carbamate
N-(tert-Butoxycarbonyl)-1,5-pentanediamine
N-Boc-1,5-diaminopentane
tert-butyl N-(5-aminopentyl)carbamate
N-Boc-1,5-pentanediamine
2-Methyl-2-propanyl (5-aminopentyl)carbamate
Carbamic acid, N-(5-aminopentyl)-, 1,1-dimethylethyl ester
N-(5-Aminoamyl)carbamic Acid tert-Butyl Ester
MFCD00210020
N-(tert-Butoxycarbonyl)-1,5-diaminopentane
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Chemsrc provides N-Boc-1,5-diaminopentane(CAS#:51644-96-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of N-Boc-1,5-diaminopentane are included as well.>> amp version: N-Boc-1,5-diaminopentane

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