Bilobetin

Modify Date: 2024-01-21 11:23:32

Bilobetin Structure
Bilobetin structure
Common Name Bilobetin
CAS Number 521-32-4 Molecular Weight 552.484
Density 1.6±0.1 g/cm3 Boiling Point 869.9±65.0 °C at 760 mmHg
Molecular Formula C31H20O10 Melting Point 296-298ºC
MSDS N/A Flash Point 291.9±27.8 °C

 Use of Bilobetin


Bilobetin, an active component of Ginkgo biloba, can reduce blood lipids and improve the effects of insulin. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylation, nuclear translocation and activity of PPARα accompanied by elevated cAMP level and PKA activity[1].

 Names

Name 8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Synonym More Synonyms

 Bilobetin Biological Activity

Description Bilobetin, an active component of Ginkgo biloba, can reduce blood lipids and improve the effects of insulin. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylation, nuclear translocation and activity of PPARα accompanied by elevated cAMP level and PKA activity[1].
Related Catalog
Target

PPARα

PKA

References

[1]. Kou XH, et al. Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet. Br J Pharmacol. 2012 Apr;165(8):2692-706.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 869.9±65.0 °C at 760 mmHg
Melting Point 296-298ºC
Molecular Formula C31H20O10
Molecular Weight 552.484
Flash Point 291.9±27.8 °C
Exact Mass 552.105652
PSA 170.80000
LogP 4.20
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.750

 Safety Information

Hazard Codes Xi

 Synonyms

3''',8-Biflavone,4',5,5'',7,7''-pentahydroxy-4'''-methoxy
4'-monomethylamentoflavone
4'-methylamentoflavone
8-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
Bilobetin
4H-1-Benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-
4'-O-methylamentoflavone
Top Suppliers:I want be here
  • BioBioPha
  • China
  • Product Name: Bilobetin
  • Price: ¥Inquiry/10mg
  • Purity: 98.0%
  • Stocking Period: 1 Day
  • Contact: Xueping-Zheng



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Price: ¥3055/5mg

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