Quercitrin

Modify Date: 2024-01-02 15:42:54

Quercitrin structure	Common Name	Quercitrin
	CAS Number	522-12-3	Molecular Weight	448.377
	Density	1.8±0.1 g/cm3	Boiling Point	814.0±65.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₂₀O₁₁	Melting Point	174-183ºC
	MSDS	Chinese USA	Flash Point	288.3±27.8 °C

Use of Quercitrin

Quercitrin is a natural compound found in Tartary buckwheat with a potential anti-inflammation effect that is used to treat heart and vascular conditions.IC50 value:Target:In vitro: There were significant increases in caspase-3 activity, loss of MMP, and increases in the apoptotic cell population in response to quercitrin in DLD-1 colon cancer cells in a time- and dose-dependent manner. [1] In vivo: ICR mice received CCl4 intraperitoneally with or without quercitrin co-administration for 4 weeks. Data showed that quercitrin significantly suppressed the elevation of reactive oxygen species (ROS) production and malondialdehyde (MDA) content, reduced tissue plasminogen activator (t-PA) activity, enhanced the antioxidant enzyme activities and abrogated cytochrome P450 2E1 (CYP2E1) induction in mouse brains. [2]

Name	quercitrin
Synonym	More Synonyms

Description	Quercitrin is a natural compound found in Tartary buckwheat with a potential anti-inflammation effect that is used to treat heart and vascular conditions.IC50 value:Target:In vitro: There were significant increases in caspase-3 activity, loss of MMP, and increases in the apoptotic cell population in response to quercitrin in DLD-1 colon cancer cells in a time- and dose-dependent manner. [1] In vivo: ICR mice received CCl4 intraperitoneally with or without quercitrin co-administration for 4 weeks. Data showed that quercitrin significantly suppressed the elevation of reactive oxygen species (ROS) production and malondialdehyde (MDA) content, reduced tissue plasminogen activator (t-PA) activity, enhanced the antioxidant enzyme activities and abrogated cytochrome P450 2E1 (CYP2E1) induction in mouse brains. [2]
Related Catalog	Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> MAPK/ERK Pathway >> Ribosomal S6 Kinase (RSK) Natural Products >> Flavonoids Research Areas >> Inflammation/Immunology
References	[1]. Cincin ZB, et al. Apoptotic Effects of Quercitrin on DLD-1 Colon Cancer Cell Line. Pathol Oncol Res. 2015 Apr;21(2):333-8. [2]. Ma JQ, et al. Quercitrin offers protection against brain injury in mice by inhibiting oxidative stress and inflammation. Food Funct. 2016 Jan 20;7(1):549-56. [3]. Li W, et al. Quercitrin ameliorates the development of systemic lupus erythematosus-like disease in a chronic graft-versus-host murine model. Am J Physiol Renal Physiol. 2016 Feb 24:ajprenal.00249.2015.

Description

Related Catalog

Signaling Pathways >> Autophagy >> Autophagy

Signaling Pathways >> MAPK/ERK Pathway >> Ribosomal S6 Kinase (RSK)

Natural Products >> Flavonoids

Research Areas >> Inflammation/Immunology

References

[1]. Cincin ZB, et al. Apoptotic Effects of Quercitrin on DLD-1 Colon Cancer Cell Line. Pathol Oncol Res. 2015 Apr;21(2):333-8.

[2]. Ma JQ, et al. Quercitrin offers protection against brain injury in mice by inhibiting oxidative stress and inflammation. Food Funct. 2016 Jan 20;7(1):549-56.

[3]. Li W, et al. Quercitrin ameliorates the development of systemic lupus erythematosus-like disease in a chronic graft-versus-host murine model. Am J Physiol Renal Physiol. 2016 Feb 24:ajprenal.00249.2015.

Density	1.8±0.1 g/cm3
Boiling Point	814.0±65.0 °C at 760 mmHg
Melting Point	174-183ºC
Molecular Formula	C₂₁H₂₀O₁₁
Molecular Weight	448.377
Flash Point	288.3±27.8 °C
Exact Mass	448.100555
PSA	190.28000
LogP	2.17
Vapour Pressure	0.0±3.1 mmHg at 25°C
Index of Refraction	1.776
Storage condition	2-8°C

Quercitrin MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UZ5950000

CHEMICAL NAME :: Quercitrin

CAS REGISTRY NUMBER :: 522-12-3

BEILSTEIN REFERENCE NO. :: 0068135

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C21-H20-O11

MOLECULAR WEIGHT :: 448.41

WISWESSER LINE NOTATION :: T66 BO EVJ CR CQ DQ& GQ IQ DO- BT6OTJ CQ DQ EQ F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 166 nmol/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 54,297,1978

Hazard Codes	Xi
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	UZ5950000

2''-O-Galloylqu...

CAS#:80229-08-9

Quercitrin

CAS#:522-12-3

Literature: Isobe, Takahiko; Kanazawa, Keiji; Fujimura, Makoto; Noda, Yukinao Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 10 p. 3239

Precursor 1
CAS#:80229-08-9 2''-O-Galloylqu...
DownStream 4
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Separation of the antioxidant compound quercitrin from Lindera obtusiloba Blume and its antimelanogenic effect on B16F10 melanoma cells.

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quercetin 3-O-α-L-rhamnopyranoside

quercetin-3-L-rhamnoside

3-O-α-rhamnosylquercetine

Quercetin 3-O-L-rhamnoside

Quercitroside

QUERCETIN 3-L-RHAMNOSIDE

EINECS 208-322-5

Thujin

3,3',4',5,7-Pentahydroxyflavone 3-(6-deoxy-a-L-mannopyranoside)

4H-1-Benzopyran-4-one, 3-((6-deoxy-α-L-mannopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4H-chromen-4-on

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4H-chromen-4-one

Quercetin 3-O-α-L-rhamnoside

2-(3,4-Dihydroxyphényl)-5,7-dihydroxy-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}-4H-chromén-4-one

Quercetin-3-O-α-L-rhamnopyranoside

3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-benzopyran-4-one

Quercimelin

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl-6-deoxy-α-L-mannopyranoside

Quercetin-3-rhamnoside

4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-

Quercetrin

FLAVIN

Quercetin-3-O-rhamnoside

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-α-L-mannopyranoside

usafcf-2

quercetin 3-O-rhamnoside

MFCD00016932

3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one

Quercitrin

quercetin 3-rhamnoside

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Quercitrin
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BioBioPha
China
Product Name: Quercitrin
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Quercitrin
Price: ￥448.0/20mg
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DC Chemicals Limited
China
Product Name: Quercitrin
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Taiwan Oyi peptide Co. Ltd
China
Product Name: QUERCITRIN
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Delivery: 1 Day
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Quercitrin

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