9-pentofuranosyl-9H-purin-6-amine

Modify Date: 2024-01-12 15:30:57

9-pentofuranosyl-9H-purin-6-amine Structure
9-pentofuranosyl-9H-purin-6-amine structure
Common Name 9-pentofuranosyl-9H-purin-6-amine
CAS Number 524-69-6 Molecular Weight 267.24
Density 2.08g/cm3 Boiling Point 676.3ºC at 760 mmHg
Molecular Formula C10H13N5O4 Melting Point 257.0-257.5ºC (0.4 H2O)
MSDS N/A Flash Point 362.8ºC

 Use of 9-pentofuranosyl-9H-purin-6-amine


9-(β-D-Xylofuranosyl)adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

 Names

Name 9-β-D-xylofuranosyladenine
Synonym More Synonyms

 9-pentofuranosyl-9H-purin-6-amine Biological Activity

Description 9-(β-D-Xylofuranosyl)adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

[2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

 Chemical & Physical Properties

Density 2.08g/cm3
Boiling Point 676.3ºC at 760 mmHg
Melting Point 257.0-257.5ºC (0.4 H2O)
Molecular Formula C10H13N5O4
Molecular Weight 267.24
Flash Point 362.8ºC
Exact Mass 267.09700
PSA 139.54000
Index of Refraction 1.907

 Precursor & DownStream

Precursor  0

DownStream  2

 Synonyms

Adenine xyloside
Xylosyl a
Xylosyladenine
9-.β.-D-Xylofuranosyladenine
9-beta-D-xylofuranosyladenine