Oxeladin (citrate)

Modify Date: 2024-01-02 20:03:44

Oxeladin (citrate) Structure
Oxeladin (citrate) structure
Common Name Oxeladin (citrate)
CAS Number 52432-72-1 Molecular Weight 527.60400
Density N/A Boiling Point 609.1ºC at 760 mmHg
Molecular Formula C26H41NO10 Melting Point 90-91°
MSDS Chinese USA Flash Point 322.2ºC
Symbol GHS06
GHS06
Signal Word Danger

 Use of Oxeladin (citrate)


Oxeladin citrate is a cough suppressant, is a highly potent and effective drug used to treat all types of cough of various etiologies.

 Names

Name 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate,2-hydroxypropane-1,2,3-tricarboxylic acid
Synonym More Synonyms

 Oxeladin (citrate) Biological Activity

Description Oxeladin citrate is a cough suppressant, is a highly potent and effective drug used to treat all types of cough of various etiologies.
Related Catalog

 Chemical & Physical Properties

Boiling Point 609.1ºC at 760 mmHg
Melting Point 90-91°
Molecular Formula C26H41NO10
Molecular Weight 527.60400
Flash Point 322.2ºC
Exact Mass 527.27300
PSA 170.90000
LogP 2.39750
Storage condition -20℃
Water Solubility Freely soluble in water, slightly to very slightly soluble in ethyl acetate.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ET1760000
CHEMICAL NAME :
Butyric acid, 2-ethyl-2-phenyl-, 2-(2-(diethylamino)ethoxy)ethyl ester, citrate
CAS REGISTRY NUMBER :
52432-72-1
LAST UPDATED :
198910
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C20-H33-N-O3.C6-H8-O7
MOLECULAR WEIGHT :
527.68
WISWESSER LINE NOTATION :
2X2&R&VO2O2N2&2 &QV1XQVQ1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
183 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,157,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
130 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,157,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
244 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 82,1314,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
13 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,157,1982

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301 + H311 + H331
Precautionary Statements Missing Phrase - N15.00950417-P261-P280-P302 + P352 + P312-P304 + P340 + P312-P403 + P233
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T
Risk Phrases 23/24/25
Safety Phrases 36/37/39-45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS ET1760000

 Articles4

More Articles
High performance liquid chromatographic determination of oxeladin citrate and oxybutynin hydrochloride and their degradation products.

Il Farmaco 60(8) , 689-99, (2005)

Two high performance liquid chromatographic (HPLC) methods are presented for the determination of oxeladin citrate (OL) and oxybutynin hydrochloride (OB) and their degradation products. The first meth...

Determination of oxeladin in human sera by gas--liquid chromatography with thermionic detection.

J. Chromatogr. A. 225(2) , 463-8, (1981)

[Determination of oxeladin citrate in drug combinations].

Pharmazie 37(1) , 76-7, (1982)

 Synonyms

Bio-0361
HMS3264M05
Oxeladin citrate salt
oxeladin dihydrogen citrate
oxeladin citrate
Oxeladin-zitrat
Oxeladin (citrate)