β-Nor-lapachone

Modify Date: 2024-01-09 22:44:18

β-Nor-lapachone Structure
β-Nor-lapachone structure
Common Name β-Nor-lapachone
CAS Number 52436-88-1 Molecular Weight 228.24
Density N/A Boiling Point N/A
Molecular Formula C14H12O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of β-Nor-lapachone


β-Nor-lapachone is a Candida glabrata antibiofilm agent. β-Nor-lapachone can stimulate ROS production, inhibits efflux activity, adhesion, biofilm formation and the metabolism of mature biofilms of Candida glabrata. β-Nor-lapachone has antifungal activity[1].

 Names

Name 2,2-dimethyl-3H-benzo[g][1]benzofuran-4,5-dione
Synonym More Synonyms

 β-Nor-lapachone Biological Activity

Description β-Nor-lapachone is a Candida glabrata antibiofilm agent. β-Nor-lapachone can stimulate ROS production, inhibits efflux activity, adhesion, biofilm formation and the metabolism of mature biofilms of Candida glabrata. β-Nor-lapachone has antifungal activity[1].
Related Catalog
Target

Candida glabrata, ROS[1]

References

[1]. Clemente de Moraes D, et al. Effects of β-lapachone and β-nor-lapachone on multidrug efflux transporters and biofilms of Candida glabrata. Bioorg Med Chem. 2022;63:116749.

 Chemical & Physical Properties

Molecular Formula C14H12O3
Molecular Weight 228.24
Exact Mass 228.07900
PSA 43.37000
LogP 2.36200

 Synthetic Route

 Synonyms

Naphtho[1,2-b]furan-4,5-dione,2,3-dihydro-2,2-dimethyl