pyridoxamine phosphate
pyridoxamine phosphate structure
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Common Name | pyridoxamine phosphate | ||
|---|---|---|---|---|
| CAS Number | 529-96-4 | Molecular Weight | 248.17300 | |
| Density | 1.559g/cm3 | Boiling Point | 607.3ºC at 760 mmHg | |
| Molecular Formula | C8H13N2O5P | Melting Point | N/A | |
| MSDS | USA | Flash Point | 321.1ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of pyridoxamine phosphatePyridoxamine 5′-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5′-phosphate is the aminated form of pyridoxal 5'-phosphate hydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5′-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate[1]. |
Summary: Pyridoxamine 5'-phosphate, Chinese name: 吡哆胺-5′-磷酸盐, CAS number: 529-96-4, molecular formula: C8H13N2O5P, molecular weight: 248.17300, For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | pyridoxamine 5'-phosphate |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Pyridoxamine 5′-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5′-phosphate is the aminated form of pyridoxal 5'-phosphate hydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5′-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate[1]. |
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| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | Pyridoxamine 5′-phosphate can be transformed from pyridoxal 5′-phosphate. Purified His-tagged omega-TA CV2025 from Chromobacterium violaceum is capable of complete conversion of pyridoxal 5′-phosphate to pyridoxamine 5′-phosphate in the presence of (S)-α-methylbenzylamine (MBA) as the amine donor. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.559g/cm3 |
|---|---|
| Boiling Point | 607.3ºC at 760 mmHg |
| Molecular Formula | C8H13N2O5P |
| Molecular Weight | 248.17300 |
| Flash Point | 321.1ºC |
| Exact Mass | 248.05600 |
| PSA | 135.71000 |
| LogP | 0.86390 |
| Index of Refraction | 1.622 |
| InChIKey | ZMJGSOSNSPKHNH-UHFFFAOYSA-N |
| SMILES | Cc1ncc(COP(=O)(O)O)c(CN)c1O |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
| RTECS | UT4710000 |
| HS Code | 2933399090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 9 | |
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| DownStream 2 | |
CAS#:524-36-7
CAS#:54-47-7
CAS#:20905-66-2
CAS#:58-56-0
CAS#:75-04-7
CAS#:302-72-7
CAS#:56-86-0
CAS#:7758-99-8
CAS#:32653-39-7
CAS#:954-27-8This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Fungal recognition enhances mannose receptor shedding through dectin-1 engagement.
J. Biol. Chem. 286(10) , 7822-9, (2011) The mannose receptor (MR) is an endocytic type I membrane molecule with a broad ligand specificity that is involved in both hemostasis and pathogen recognition. Membrane-anchored MR is cleaved by a me... |
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The intestine plays a substantial role in human vitamin B6 metabolism: a Caco-2 cell model.
PLoS ONE 8(1) , e54113, (2013) Vitamin B6 is present in various forms (vitamers) in the diet that need to be metabolized to pyridoxal phosphate (PLP), the active cofactor form of vitamin B6. In literature, the liver has been report... |
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Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.
Neurochem. Int. 59 , 518-524, (2011) Branched-chain amino acids (BCAAs) catabolism follows sequential reactions and their metabolites intersect with other metabolic pathways. The initial enzymes in BCAA metabolism, the mitochondrial bran... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Pyridoxamine,3-(dihydrogen phosphate) |
| [4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methyl dihydrogen phosphate |
| pyrodoxylamine-5'-phosphate |
| Pyridoxamine phosphate [JAN] |
| pyridoxamine phosphate |
| Pyridoxamine-P |
| 4-Aminomethyl-5-hydroxy-6-methyl-3-pyridylmethyl phosphate |
| Pyridoxamine,dihydrogen phosphate |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of pyridoxamine 5'-phosphate? |
| A: Polar surface area (PSA) of pyridoxamine 5'-phosphate is 135.71000. |
| Q: What is the CAS number of pyridoxamine 5'-phosphate? |
| A: CAS number of pyridoxamine 5'-phosphate is 529-96-4. |
| Q: What English synonyms does pyridoxamine 5'-phosphate have? |
| A: English synonyms of pyridoxamine 5'-phosphate: Pyridoxamine,3-(dihydrogen phosphate), [4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methyl dihydrogen phosphate, pyrodoxylamine-5'-phosphate, Pyridoxamine phosphate [JAN], pyridoxamine phosphate, Pyridoxamine-P, 4-Aminomethyl-5-hydroxy-6-methyl-3-pyridylmethyl phosphate, Pyridoxamine,dihydrogen phosphate. |
| Q: What is the LogP of pyridoxamine 5'-phosphate? |
| A: LogP of pyridoxamine 5'-phosphate is 0.86390. |
| Q: What is the SMILES notation of pyridoxamine 5'-phosphate? |
| A: SMILES notation of pyridoxamine 5'-phosphate is Cc1ncc(COP(=O)(O)O)c(CN)c1O. |
| Q: What are the upstream materials of pyridoxamine 5'-phosphate? |
| A: Related upstream materials(CAS) of pyridoxamine 5'-phosphate: 524-36-7;54-47-7;20905-66-2;58-56-0;75-04-7;302-72-7;56-86-0;7758-99-8;32653-39-7. |
| Q: What is the boiling point of pyridoxamine 5'-phosphate? |
| A: Boiling point of pyridoxamine 5'-phosphate is 607.3ºC at 760 mmHg. |
| Q: What is the English name of pyridoxamine 5'-phosphate? |
| A: The English name of pyridoxamine 5'-phosphate is pyridoxamine 5'-phosphate. |
| Q: What are the downstream products of pyridoxamine 5'-phosphate? |
| A: Related downstream products(CAS) of pyridoxamine 5'-phosphate: 54-47-7;954-27-8. |
| Q: What are the uses of pyridoxamine 5'-phosphate? |
| A: Main uses of pyridoxamine 5'-phosphate: Pyridoxamine 5′-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5′-phosphate is the aminated form of pyridoxal 5'-phosphate hydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5′-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate[1]. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |