Coproporphyrin I

Modify Date: 2024-01-09 11:44:24

Coproporphyrin I Structure
Coproporphyrin I structure
Common Name Coproporphyrin I
CAS Number 531-14-6 Molecular Weight 654.70900
Density N/A Boiling Point N/A
Molecular Formula C36H38N4O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Coproporphyrin I


Coproporphyrin I is an endogenous metabolite present in Urine and Blood that can be used for the research of Liver Disease and Porphyria[1][2][3][4].

 Names

Name 3-[7,12,17-tris(2-carboxyethyl)-3,8,13,18-tetramethyl-21,22-dihydroporphyrin-2-yl]propanoic acid
Synonym More Synonyms

 Coproporphyrin I Biological Activity

Description Coproporphyrin I is an endogenous metabolite present in Urine and Blood that can be used for the research of Liver Disease and Porphyria[1][2][3][4].
Related Catalog
In Vitro Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
References

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.  

[2]. Zuijderhoudt FM, et al. On accuracy and precision of a HPLC method for measurement of urine porphyrin concentrations. Clin Chem Lab Med. 2000 Mar;38(3):227-30.  

[3]. Hindmarsh JT, et al. Biochemical differentiation of the porphyrias. Clin Biochem. 1999 Nov;32(8):609-19.  

[4]. MAGNUS IA, et al. Erythropoietic protoporphyria. A new porphyria syndrome with solar urticaria due to protoporphyrinaemia. Lancet. 1961 Aug 26;2(7200):448-51.  

 Chemical & Physical Properties

Molecular Formula C36H38N4O8
Molecular Weight 654.70900
Exact Mass 654.26900
PSA 205.50000
LogP 3.09360
Index of Refraction 1.638

 Synthetic Route

 Synonyms

Coproporphyrin I
coproporphyrin-I tetracarboxylic acid
coproporphyrine I
coproporphyrin I-3,8,13,18-tetramethyl-21H,23H-porphine-2,7,12,17-tetrapropionic acid
3,8,13,18-tetramethyl-21H,23H-porphyrin 2,7,12,17-tetrapropionic acid
3,8,13,18-Tetramethyl-21H,23H-porphine-2,7,12,17-tetrapropionic acid
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