Euparin

Modify Date: 2026-07-04 18:23:58

Euparin Structure
Euparin structure
Common Name Euparin
CAS Number 532-48-9 Molecular Weight 216.23300
Density 1.187g/cm3 Boiling Point 258.3ºC at 760mmHg
Molecular Formula C13H12O3 Melting Point 152-153℃
MSDS N/A Flash Point 110ºC

 Use of Euparin


Euparin, a monomeric compound of Benzofuran, is a reactive oxygen species (ROS) inhibitor. Euparin shows antiviral activity against poliovirus, and also has antidepressant effects[1][2].

Summary: Euparin, Chinese name as Zelan Su, CAS number 532-48-9, molecular formula C13H12O3, molecular weight 216.23300. It appears as yellow powder with a melting point of 152-153℃. For research-use only, not for medical or clinical usage.


 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone
Synonym More Synonyms

 Euparin Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Euparin, a monomeric compound of Benzofuran, is a reactive oxygen species (ROS) inhibitor. Euparin shows antiviral activity against poliovirus, and also has antidepressant effects[1][2].
Related Catalog
In Vitro In Vero cells, Euparin shows antiviral activity against poliovirus types 1, 2, and 3 with EC50 values of 0.47 µg/mL, 0.12 µg/mL, and 0.15 µg/mL, respectively[1].
In Vivo Euparin (8, 16 and 32 mg/kg) reduces depression-like behavior in Chronic Unpredictable Mild Stress (CUMS) model of mice. All doses of Euparin are found to increase the contents of monoamine neurotransmitter and decrease monoamine oxidase and reactive oxygen species (ROS) levels in brain of depression mice. Euparin restores CUMS-induced decrease of Spermidine/Spermine N1-Acetyltransferase 1 (SAT1), N-methyl-D-aspartate receptor subtype 2B (NMDAR2B) and brain derived neurotrophic factor (BDNF) expression[2].
References

[1]. aría Florencia Visintini Jaime, et al. Antipoliovirus Activity of the Organic Extract of Eupatorium buniifolium: Isolation of Euparin as an Active Compound. Evid Based Complement Alternat Med. 2013;2013:402364.

[2]. Xu-Meng Han, et al. Antidepressant Activity of Euparin: Involvement of Monoaminergic Neurotransmitters and SAT1/NMDAR2B/BDNF Signal Pathway. Biol Pharm Bull. 2020 Oct 1;43(10):1490-1500.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.187g/cm3
Boiling Point 258.3ºC at 760mmHg
Melting Point 152-153℃
Molecular Formula C13H12O3
Molecular Weight 216.23300
Flash Point 110ºC
Exact Mass 216.07900
PSA 50.44000
LogP 3.37410
Index of Refraction 1.602
InChIKey OPUFDNZTKHPZHM-UHFFFAOYSA-N
SMILES C=C(C)c1cc2cc(C(C)=O)c(O)cc2o1

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xi
HS Code 2932999099

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~83%

Euparin Structure

Euparin

CAS#:532-48-9

Learn More
Literature: Sogawa, Akihiro; Tsukayama, Masao; Nozaki, Hiroshi; Nakayama, Mitsuru Heterocycles, 1996 , vol. 43, # 1 p. 101 - 111

~%

Euparin Structure

Euparin

CAS#:532-48-9

Learn More
Literature: Sogawa, Akihiro; Tsukayama, Masao; Nozaki, Hiroshi; Nakayama, Mitsuru Heterocycles, 1996 , vol. 43, # 1 p. 101 - 111

~%

Euparin Structure

Euparin

CAS#:532-48-9

Learn More
Literature: Sogawa, Akihiro; Tsukayama, Masao; Nozaki, Hiroshi; Nakayama, Mitsuru Heterocycles, 1996 , vol. 43, # 1 p. 101 - 111

~%

Euparin Structure

Euparin

CAS#:532-48-9

Learn More
Literature: Sogawa, Akihiro; Tsukayama, Masao; Nozaki, Hiroshi; Nakayama, Mitsuru Heterocycles, 1996 , vol. 43, # 1 p. 101 - 111

~%

Euparin Structure

Euparin

CAS#:532-48-9

Learn More
Literature: Sogawa, Akihiro; Tsukayama, Masao; Nozaki, Hiroshi; Nakayama, Mitsuru Heterocycles, 1996 , vol. 43, # 1 p. 101 - 111

~%

Euparin Structure

Euparin

CAS#:532-48-9

Learn More
Literature: Sogawa, Akihiro; Tsukayama, Masao; Nozaki, Hiroshi; Nakayama, Mitsuru Heterocycles, 1996 , vol. 43, # 1 p. 101 - 111

~%

Euparin Structure

Euparin

CAS#:532-48-9

Learn More
Literature: Scannell, Ralph T.; Stevenson, Robert Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2927 - 2932

~32%

Euparin Structure

Euparin

CAS#:532-48-9

Learn More
Literature: Scannell, Ralph T.; Stevenson, Robert Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2927 - 2932

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 EuparinBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Toxicity in brine shrimp
Source: ChEMBL
Target: Artemia
External Id: CHEMBL991092
Name: Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-p1-antagonist
Name: Cytotoxicity against human A549 cells after 7 days by MTT assay
Source: ChEMBL
Target: A549
External Id: CHEMBL991091
Name: Antimicrobial activity against Trichophyton mentagrophytes ATCC 9129 by agar dilution...
Source: ChEMBL
Target: Trichophyton mentagrophytes
External Id: CHEMBL991094
Name: Phytogrowth-inhibitory activity against Amaranthus hypochondriacus assessed as inhibi...
Source: ChEMBL
Target: Amaranthus hypochondriacus
External Id: CHEMBL991093
Name: Phytogrowth-inhibitory activity against Echinochloa crus-galli assessed as inhibition...
Source: ChEMBL
Target: Echinochloa crus-galli
External Id: CHEMBL991088
Name: ERK5 transcriptional activity HTS
Source: 24565
Target: N/A
External Id: ERK5 transcriptional activity-HTS
Name: Cytotoxicity against human HT29 cells after 7 days by MTT assay
Source: ChEMBL
Target: HT-29
External Id: CHEMBL991090
Name: Cytotoxicity against human MCF7 cells after 7 days by MTT assay
Source: ChEMBL
Target: MCF7
External Id: CHEMBL991089
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

1-(6-Hydroxy-2-isopropenyl-benzofuran-5-yl)-aethanon
5-acetyl-6-hydroxy-2-isopropenylbenzofuran
1-(6-hydroxy-2-isopropenyl-1-benzofuran-5-yl)-1-ethanone
1-[6-hydroxy-2-(1-methylethenyl)-5-benzofuranyl]-ethanone
Euparin
1-(6-hydroxy-2-isopropenyl-benzofuran-5-yl)-ethanone

 Euparin | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the uses of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone?
A: Main uses of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone: Euparin, a monomeric compound of Benzofuran, is a reactive oxygen species (ROS) inhibitor. Euparin shows antiviral activity against poliovirus, and also has antidepressant effects[1][2].
Q: What are the downstream products of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone?
A: Related downstream products(CAS) of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone: 34293-13-5.
Q: What English synonyms does 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone have?
A: English synonyms of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone: 1-(6-Hydroxy-2-isopropenyl-benzofuran-5-yl)-aethanon, 5-acetyl-6-hydroxy-2-isopropenylbenzofuran, 1-(6-hydroxy-2-isopropenyl-1-benzofuran-5-yl)-1-ethanone, 1-[6-hydroxy-2-(1-methylethenyl)-5-benzofuranyl]-ethanone, Euparin, 1-(6-hydroxy-2-isopropenyl-benzofuran-5-yl)-ethanone.
Q: What is the molecular weight of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone?
A: Molecular weight of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone is 216.23300.
Q: What is the InChIKey of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone?
A: InChIKey of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone is OPUFDNZTKHPZHM-UHFFFAOYSA-N.
Q: What is the boiling point of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone?
A: Boiling point of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone is 258.3ºC at 760mmHg.
Q: What is the melting point of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone?
A: Melting point of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone is 152-153℃.
Q: What are the upstream materials of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone?
A: Related upstream materials(CAS) of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone: 89-84-9;22877-01-6;62069-33-4;173992-03-5;62069-34-5;56964-06-8.
Q: What is the polar surface area (PSA) of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone?
A: Polar surface area (PSA) of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone is 50.44000.
Q: What is the English name of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone?
A: The English name of 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone is 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone.

 Euparinfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
BioBioPha
naturewill
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